Lymphocyte phenotyping in untreated children patients with chronic allergic asthma

This study aimed to isolate and phenotype lymphocytes in untreated children patients with chronic allergic asthma. To reach such aim the study involved (25) patients from children (17 male and 9 female) whom their ages where between (3-10) years, in addition to (15) apparently healthy children (9 ma...

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Main Author: Baghdad Science Journal
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2010-03-01
Series:مجلة بغداد للعلوم
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Online Access:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2860
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author Baghdad Science Journal
author_facet Baghdad Science Journal
author_sort Baghdad Science Journal
collection DOAJ
description This study aimed to isolate and phenotype lymphocytes in untreated children patients with chronic allergic asthma. To reach such aim the study involved (25) patients from children (17 male and 9 female) whom their ages where between (3-10) years, in addition to (15) apparently healthy children (9 male and 6 female) in the same ages involved as control group. The data demonstrated that there was a significant increase in the mean percentages of T-lymphocytes (CD3+ cells) in the peripheral blood of patients (66.75±0.29)**, in comparison with control group (43.58±0.19), a significant increase in the mean percentages of T-helper lymphocytes (CD4+ cells) in the peripheral blood of patients (51.14±0.55), in comparison with control group (39.17±0.23) and the mean percentages of B-lymphocytes (CD20+ cells) was also increased significantly in the peripheral blood of patients (29.63±0.20) when it compared with the mean percentages of the same cells in control group (18.60±0.80). Besides a significant decrease in the mean percentages of T-suppressor lymphocytes (CD8+ cells) in the peripheral blood of patients (11.31±0.05), in comparison with control group (16.42±0.15). Finally the results of this study showed a significant increase in the mean percentages of the ratio of (CD4+ cells/CD8+ cells) in the peripheral blood of patients (55.34±0.41), in comparison with control group (31.25±0.09).
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publisher University of Baghdad, College of Science for Women
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series مجلة بغداد للعلوم
spelling doaj-art-549ebca855cf423f999a13a2bd9a96c92025-08-20T03:56:12ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862010-03-017110.21123/bsj.7.1.382-388Lymphocyte phenotyping in untreated children patients with chronic allergic asthmaBaghdad Science JournalThis study aimed to isolate and phenotype lymphocytes in untreated children patients with chronic allergic asthma. To reach such aim the study involved (25) patients from children (17 male and 9 female) whom their ages where between (3-10) years, in addition to (15) apparently healthy children (9 male and 6 female) in the same ages involved as control group. The data demonstrated that there was a significant increase in the mean percentages of T-lymphocytes (CD3+ cells) in the peripheral blood of patients (66.75±0.29)**, in comparison with control group (43.58±0.19), a significant increase in the mean percentages of T-helper lymphocytes (CD4+ cells) in the peripheral blood of patients (51.14±0.55), in comparison with control group (39.17±0.23) and the mean percentages of B-lymphocytes (CD20+ cells) was also increased significantly in the peripheral blood of patients (29.63±0.20) when it compared with the mean percentages of the same cells in control group (18.60±0.80). Besides a significant decrease in the mean percentages of T-suppressor lymphocytes (CD8+ cells) in the peripheral blood of patients (11.31±0.05), in comparison with control group (16.42±0.15). Finally the results of this study showed a significant increase in the mean percentages of the ratio of (CD4+ cells/CD8+ cells) in the peripheral blood of patients (55.34±0.41), in comparison with control group (31.25±0.09).http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2860"The mean percentage ± standard error is used to describe the results"
spellingShingle Baghdad Science Journal
Lymphocyte phenotyping in untreated children patients with chronic allergic asthma
مجلة بغداد للعلوم
"The mean percentage ± standard error is used to describe the results"
title Lymphocyte phenotyping in untreated children patients with chronic allergic asthma
title_full Lymphocyte phenotyping in untreated children patients with chronic allergic asthma
title_fullStr Lymphocyte phenotyping in untreated children patients with chronic allergic asthma
title_full_unstemmed Lymphocyte phenotyping in untreated children patients with chronic allergic asthma
title_short Lymphocyte phenotyping in untreated children patients with chronic allergic asthma
title_sort lymphocyte phenotyping in untreated children patients with chronic allergic asthma
topic "The mean percentage ± standard error is used to describe the results"
url http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2860
work_keys_str_mv AT baghdadsciencejournal lymphocytephenotypinginuntreatedchildrenpatientswithchronicallergicasthma