Targeting glycolysis: exploring a new frontier in glioblastoma therapy

Targeting glycolysis: exploring a new frontier in glioblastoma therapy

Glioblastoma(GBM) is a highly malignant primary central nervous system tumor that poses a significant threat to patient survival due to its treatment resistance and rapid recurrence.Current treatment options, including maximal safe surgical resection, radiotherapy, and temozolomide (TMZ) chemotherap...

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Bibliographic Details
Main Authors: Lu Yang, Sijia Li, Lei Yu, Jiao Leng, Na Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
glioblastoma
glycolytic metabolic reprogramming
lactate
tumor microenvironment
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1522392/full
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