Oral Rehydration Therapy: WHO at 40, ORT at 30
Oral rehydration therapy may prove to be mankind's most significant therapeutic advance this century. Diarrheal disease remains the number one killer of children in the world and is a major cause of illness within Canada and other developed countries. Since its discovery 30 years ago, oral rehy...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1989-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1989/138105 |
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| _version_ | 1849700659168804864 |
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| author | Jonathan LaPook Richard N. Fedorak |
| author_facet | Jonathan LaPook Richard N. Fedorak |
| author_sort | Jonathan LaPook |
| collection | DOAJ |
| description | Oral rehydration therapy may prove to be mankind's most significant
therapeutic advance this century. Diarrheal disease remains the number one
killer of children in the world and is a major cause of illness within Canada and other
developed countries. Since its discovery 30 years ago, oral rehydration therapy, comprising
glucose, salt and water, has been a simple and low cost treatment for people
with life threatening diarrheal disease. Recent developments in solutions for oral
rehydration therapy have led to the recognition chat the existing World Health Organization
glucose based oral replacement salt could be improved. ln commercially
available rehydration solutions, the sodium concentration has been lowered to reduce
hypernatremia in noncholera induced diarrhea. Citrate has replaced bicarbonate as
the base in oral replacement solutions to pro long shelf life. Organic substrates to
replace glucose and enhance intestinal fluid and electrolyte absorption without osmotic
penalty are being examined. However, their acceptance and proper utilization in
developing countries remains to be determined. |
| format | Article |
| id | doaj-art-5497800a16b741be9ddfa198c33572a8 |
| institution | DOAJ |
| issn | 0835-7900 |
| language | English |
| publishDate | 1989-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-5497800a16b741be9ddfa198c33572a82025-08-20T03:18:12ZengWileyCanadian Journal of Gastroenterology0835-79001989-01-013171410.1155/1989/138105Oral Rehydration Therapy: WHO at 40, ORT at 30Jonathan LaPook0Richard N. Fedorak1Department of Medicine, Division of Gastroenterology, College of Physicians and Surgeons of Columbia University, New York, USADepartment of Medicine, Division of Gastroenterology, University of Alberta, Edmonton, Alberta, CanadaOral rehydration therapy may prove to be mankind's most significant therapeutic advance this century. Diarrheal disease remains the number one killer of children in the world and is a major cause of illness within Canada and other developed countries. Since its discovery 30 years ago, oral rehydration therapy, comprising glucose, salt and water, has been a simple and low cost treatment for people with life threatening diarrheal disease. Recent developments in solutions for oral rehydration therapy have led to the recognition chat the existing World Health Organization glucose based oral replacement salt could be improved. ln commercially available rehydration solutions, the sodium concentration has been lowered to reduce hypernatremia in noncholera induced diarrhea. Citrate has replaced bicarbonate as the base in oral replacement solutions to pro long shelf life. Organic substrates to replace glucose and enhance intestinal fluid and electrolyte absorption without osmotic penalty are being examined. However, their acceptance and proper utilization in developing countries remains to be determined.http://dx.doi.org/10.1155/1989/138105 |
| spellingShingle | Jonathan LaPook Richard N. Fedorak Oral Rehydration Therapy: WHO at 40, ORT at 30 Canadian Journal of Gastroenterology |
| title | Oral Rehydration Therapy: WHO at 40, ORT at 30 |
| title_full | Oral Rehydration Therapy: WHO at 40, ORT at 30 |
| title_fullStr | Oral Rehydration Therapy: WHO at 40, ORT at 30 |
| title_full_unstemmed | Oral Rehydration Therapy: WHO at 40, ORT at 30 |
| title_short | Oral Rehydration Therapy: WHO at 40, ORT at 30 |
| title_sort | oral rehydration therapy who at 40 ort at 30 |
| url | http://dx.doi.org/10.1155/1989/138105 |
| work_keys_str_mv | AT jonathanlapook oralrehydrationtherapywhoat40ortat30 AT richardnfedorak oralrehydrationtherapywhoat40ortat30 |