Evaluation of the bone structure surrounding photofunctionalized implants using the fractal analysis method: a split-mouth randomized clinical study

Abstract Background Implant failure may necessitate another surgical procedure to improve implant survival. Photofunctionalization(PF) with UV light is a promising method to enhance dental implant osseointegration. The study evaluates the effect of the PF on bone quality around the implants using Fr...

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Main Authors: Hamed Farsiani, Nilsun Bagis, Elif Polat Balkan, Fatma Karacaoglu, Zülal Deniz Güner, Kaan Orhan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Oral Health
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Online Access:https://doi.org/10.1186/s12903-025-06330-6
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author Hamed Farsiani
Nilsun Bagis
Elif Polat Balkan
Fatma Karacaoglu
Zülal Deniz Güner
Kaan Orhan
author_facet Hamed Farsiani
Nilsun Bagis
Elif Polat Balkan
Fatma Karacaoglu
Zülal Deniz Güner
Kaan Orhan
author_sort Hamed Farsiani
collection DOAJ
description Abstract Background Implant failure may necessitate another surgical procedure to improve implant survival. Photofunctionalization(PF) with UV light is a promising method to enhance dental implant osseointegration. The study evaluates the effect of the PF on bone quality around the implants using Fractal Dimension Analysis (FDA). Methods A total of 42 implants were placed in a split-mouth design and evaluated using FDA on panoramic radiographs taken pre- and post-operatively. Regions of interest (25 × 25 pixels) were analyzed using ImageJ. Statistical analysis used SPSS 26 with a 95% confidence level. Shapiro-Wilk test confirmed non-normal distribution. Results A statistically significant increase in Fractal dimension(FD) values was observed in the test group between pre- and post-operative images (p = 0.044). The control group showed a non-significant increase (p = 0.794). Conclusions PF appears to enhance osseointegration by improving bone microstructure as shown by increased FD values. FDA is a reliable imaging-based proxy for evaluating implant-related bone changes. Trial registration Current Controlled Trials NCT06821932 (Retrospectively registered) ( https://clinicaltrials.gov/study/NCT06821932 /2025-02-11).
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publishDate 2025-07-01
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spelling doaj-art-54870496cf044121a412b3f0f18953d82025-08-20T03:45:41ZengBMCBMC Oral Health1472-68312025-07-012511910.1186/s12903-025-06330-6Evaluation of the bone structure surrounding photofunctionalized implants using the fractal analysis method: a split-mouth randomized clinical studyHamed Farsiani0Nilsun Bagis1Elif Polat Balkan2Fatma Karacaoglu3Zülal Deniz Güner4Kaan Orhan5Faculty of Dentistry, Department of Periodontology, Ankara UnivercistyFaculty of Dentistry, Department of Periodontology, Ankara UnivercistyFaculty of Dentistry, Department of Dento Maxillofacial Radiology, Ankara UnivercistyFaculty of Dentistry, Department of Periodontology, Ankara UnivercistyFaculty of Dentistry, Department of Periodontology, Ankara UnivercistyFaculty of Dentistry, Department of Dento Maxillofacial Radiology, Ankara UnivercistyAbstract Background Implant failure may necessitate another surgical procedure to improve implant survival. Photofunctionalization(PF) with UV light is a promising method to enhance dental implant osseointegration. The study evaluates the effect of the PF on bone quality around the implants using Fractal Dimension Analysis (FDA). Methods A total of 42 implants were placed in a split-mouth design and evaluated using FDA on panoramic radiographs taken pre- and post-operatively. Regions of interest (25 × 25 pixels) were analyzed using ImageJ. Statistical analysis used SPSS 26 with a 95% confidence level. Shapiro-Wilk test confirmed non-normal distribution. Results A statistically significant increase in Fractal dimension(FD) values was observed in the test group between pre- and post-operative images (p = 0.044). The control group showed a non-significant increase (p = 0.794). Conclusions PF appears to enhance osseointegration by improving bone microstructure as shown by increased FD values. FDA is a reliable imaging-based proxy for evaluating implant-related bone changes. Trial registration Current Controlled Trials NCT06821932 (Retrospectively registered) ( https://clinicaltrials.gov/study/NCT06821932 /2025-02-11).https://doi.org/10.1186/s12903-025-06330-6PhotofunctionalizationUltraviyolet lightDental implantHydrophilic surface
spellingShingle Hamed Farsiani
Nilsun Bagis
Elif Polat Balkan
Fatma Karacaoglu
Zülal Deniz Güner
Kaan Orhan
Evaluation of the bone structure surrounding photofunctionalized implants using the fractal analysis method: a split-mouth randomized clinical study
BMC Oral Health
Photofunctionalization
Ultraviyolet light
Dental implant
Hydrophilic surface
title Evaluation of the bone structure surrounding photofunctionalized implants using the fractal analysis method: a split-mouth randomized clinical study
title_full Evaluation of the bone structure surrounding photofunctionalized implants using the fractal analysis method: a split-mouth randomized clinical study
title_fullStr Evaluation of the bone structure surrounding photofunctionalized implants using the fractal analysis method: a split-mouth randomized clinical study
title_full_unstemmed Evaluation of the bone structure surrounding photofunctionalized implants using the fractal analysis method: a split-mouth randomized clinical study
title_short Evaluation of the bone structure surrounding photofunctionalized implants using the fractal analysis method: a split-mouth randomized clinical study
title_sort evaluation of the bone structure surrounding photofunctionalized implants using the fractal analysis method a split mouth randomized clinical study
topic Photofunctionalization
Ultraviyolet light
Dental implant
Hydrophilic surface
url https://doi.org/10.1186/s12903-025-06330-6
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