The extracellular CIRP as a predictive marker for the endothelial dysfunction in chronic obstructive pulmonary disease combined with pulmonary hypertension

The extracellular CIRP as a predictive marker for the endothelial dysfunction in chronic obstructive pulmonary disease combined with pulmonary hypertension

Abstract Background Pulmonary hypertension (PH) is a serious complication of chronic obstructive pulmonary disease (COPD), distinguished by pulmonary endothelial dysfunction. The extracellular cold-inducible RNA-binding protein (eCIRP) is a damage-associated molecular pattern (DAMP) that triggers in...

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Bibliographic Details
Main Authors: Yun Yao, Haibo Jiang, Dalin Xu, Bing Zhang, Feng Yao, Wei Guo
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Pulmonary Medicine
Subjects:
COPD
PH
Inflammation
Endothelial dysfunction
eCIRP
Online Access:https://doi.org/10.1186/s12890-024-03416-9
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