Network pharmacological analysis and in vitro testing of the rutin effects on triple-negative breast cancer

This study aims to assess the potential mechanism of rutin to treat triple-negative breast cancer (TNBC) based on network pharmacology followed by in vitro experiments.

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Main Authors: Chang Cheng, Jia Ruiying, Fang Bin, Miao Yaoyao, Zhang Lili
Format: Article
Language:English
Published: De Gruyter 2025-01-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2024-1079
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author Chang Cheng
Jia Ruiying
Fang Bin
Miao Yaoyao
Zhang Lili
author_facet Chang Cheng
Jia Ruiying
Fang Bin
Miao Yaoyao
Zhang Lili
author_sort Chang Cheng
collection DOAJ
description This study aims to assess the potential mechanism of rutin to treat triple-negative breast cancer (TNBC) based on network pharmacology followed by in vitro experiments.
format Article
id doaj-art-546ac235022f417e88f424c88a2aba37
institution Kabale University
issn 2391-5463
language English
publishDate 2025-01-01
publisher De Gruyter
record_format Article
series Open Medicine
spelling doaj-art-546ac235022f417e88f424c88a2aba372025-01-14T13:23:09ZengDe GruyterOpen Medicine2391-54632025-01-0120111310.1515/med-2024-1079Network pharmacological analysis and in vitro testing of the rutin effects on triple-negative breast cancerChang Cheng0Jia Ruiying1Fang Bin2Miao Yaoyao3Zhang Lili4General Surgery Department, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, 266011, ChinaSurgical Center, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital), Qingdao, 266011, ChinaColorectal Surgery Department, Affiliated Qingdao Hiser Hospital of Qingdao University (Qingdao Hospital of Traditional Chinese Medicine), Qingdao, 266011, ChinaPulmonary Disease Department, Affiliated Qingdao Hiser Hospital of Qingdao University (Qingdao Hospital of Traditional Chinese Medicine), Qingdao, 266011, ChinaImaging Department, Affiliated Qingdao Hiser Hospital of Qingdao University (Qingdao Hospital of Traditional Chinese Medicine), Qingdao, 266011, ChinaThis study aims to assess the potential mechanism of rutin to treat triple-negative breast cancer (TNBC) based on network pharmacology followed by in vitro experiments.https://doi.org/10.1515/med-2024-1079rutintriple-negative breast cancernetwork pharmacologymechanism
spellingShingle Chang Cheng
Jia Ruiying
Fang Bin
Miao Yaoyao
Zhang Lili
Network pharmacological analysis and in vitro testing of the rutin effects on triple-negative breast cancer
Open Medicine
rutin
triple-negative breast cancer
network pharmacology
mechanism
title Network pharmacological analysis and in vitro testing of the rutin effects on triple-negative breast cancer
title_full Network pharmacological analysis and in vitro testing of the rutin effects on triple-negative breast cancer
title_fullStr Network pharmacological analysis and in vitro testing of the rutin effects on triple-negative breast cancer
title_full_unstemmed Network pharmacological analysis and in vitro testing of the rutin effects on triple-negative breast cancer
title_short Network pharmacological analysis and in vitro testing of the rutin effects on triple-negative breast cancer
title_sort network pharmacological analysis and in vitro testing of the rutin effects on triple negative breast cancer
topic rutin
triple-negative breast cancer
network pharmacology
mechanism
url https://doi.org/10.1515/med-2024-1079
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AT jiaruiying networkpharmacologicalanalysisandinvitrotestingoftherutineffectsontriplenegativebreastcancer
AT fangbin networkpharmacologicalanalysisandinvitrotestingoftherutineffectsontriplenegativebreastcancer
AT miaoyaoyao networkpharmacologicalanalysisandinvitrotestingoftherutineffectsontriplenegativebreastcancer
AT zhanglili networkpharmacologicalanalysisandinvitrotestingoftherutineffectsontriplenegativebreastcancer