The Impact of a Manufacturing Process on the Stability of Microcrystalline Long-Acting Injections: A Case Study on Aripiprazole Monohydrate

The Impact of a Manufacturing Process on the Stability of Microcrystalline Long-Acting Injections: A Case Study on Aripiprazole Monohydrate

<b>Background/Objectives:</b> Long-acting injections (LAIs) are innovative drug delivery systems that improve patient compliance by maintaining therapeutic drug levels over extended periods. Micro- and nanosuspensions are commonly used in LAIs to enhance bioavailability, but their thermo...

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Bibliographic Details
Main Authors:	Tomasz Pietrzak, Ziemowit Szendzielorz, Joanna Borychowska, Tomasz Ratajczak, Marcin Kubisiak
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Pharmaceutics
Subjects:	long-acting injection (LAI) stability bead milling sterilization high-shear homogenization
Online Access:	https://www.mdpi.com/1999-4923/17/6/735
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