The Comparison of Clinical Epidemiology of Hospitalized Patients with COVID-19 during the Third and Fourth Waves of the Pandemic in Gorgan
Background. COVID-19 has turned into a global public health crisis. This study intended to compare demographic characteristics, disease severity, treatment methods, and clinical outcomes in hospitalized patients with COVID-19 during the third and fourth waves of the pandemic in Golestan Province, Ir...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2022/9634241 |
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| author | Samira Eshghinia Rahmat Allah Sharifi Far Naghimeh Hajimoradloo Ali Sinesepehr Ahmad Sohrsbi Mousa Imeri Amir Reza Khodanazar Kalti Erfan Rezaie Shirazi Roghieh Golsha |
| author_facet | Samira Eshghinia Rahmat Allah Sharifi Far Naghimeh Hajimoradloo Ali Sinesepehr Ahmad Sohrsbi Mousa Imeri Amir Reza Khodanazar Kalti Erfan Rezaie Shirazi Roghieh Golsha |
| author_sort | Samira Eshghinia |
| collection | DOAJ |
| description | Background. COVID-19 has turned into a global public health crisis. This study intended to compare demographic characteristics, disease severity, treatment methods, and clinical outcomes in hospitalized patients with COVID-19 during the third and fourth waves of the pandemic in Golestan Province, Iran. Methods. In this cross-sectional study, the clinical epidemiology of all COVID-19 patients, who were hospitalized in two educational hospitals in Golestan Province for 30 days from the start of the third and fourth waves of the coronavirus pandemic in 2021-2022, was assessed. Their electronic medical records were used to collect their epidemiological, demographic, laboratory, and clinical information and treatment outcome. Results. In all, 930 electronic medical records of the hospitalized patients (351 in the third wave and 579 in the fourth wave) were studied. In the third and fourth waves, 29.06% and 13.13% of the patients had severe COVID-19, respectively (P = 0.001). The number of deaths in the third wave was larger compared to the fourth wave (P = 0.015). The mean duration of hospitalization was longer in the third wave than in the fourth wave (P = 0.001). The drugs administered most in these two waves were remdesivir, dexamethasone, and heparin, and the patients who received these drugs were compared in the third and fourth waves (P = 0.001). Conclusion. The reduced rate of mortality in the fourth wave was compared to the third wave. This reduction can be attributed to the change in the national strategy adopted in terms of hospitalization criteria and treatment protocols taking into account the acquired experience, earlier hospitalization, and start of drug therapy. |
| format | Article |
| id | doaj-art-5463e1a7a4034ad6b89c6f4fc600bce3 |
| institution | Kabale University |
| issn | 1918-1493 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-5463e1a7a4034ad6b89c6f4fc600bce32025-02-03T06:01:49ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932022-01-01202210.1155/2022/9634241The Comparison of Clinical Epidemiology of Hospitalized Patients with COVID-19 during the Third and Fourth Waves of the Pandemic in GorganSamira Eshghinia0Rahmat Allah Sharifi Far1Naghimeh Hajimoradloo2Ali Sinesepehr3Ahmad Sohrsbi4Mousa Imeri5Amir Reza Khodanazar Kalti6Erfan Rezaie Shirazi7Roghieh Golsha8Biochemistry and Metabolic Disorders Research CenterInfectious Diseases Research CenterInfectious Diseases Research CenterSchool of MedicineInfectious Diseases Research CenterSchool of MedicineSchool of MedicineInfectious Diseases Research CenterInfectious Diseases Research CenterBackground. COVID-19 has turned into a global public health crisis. This study intended to compare demographic characteristics, disease severity, treatment methods, and clinical outcomes in hospitalized patients with COVID-19 during the third and fourth waves of the pandemic in Golestan Province, Iran. Methods. In this cross-sectional study, the clinical epidemiology of all COVID-19 patients, who were hospitalized in two educational hospitals in Golestan Province for 30 days from the start of the third and fourth waves of the coronavirus pandemic in 2021-2022, was assessed. Their electronic medical records were used to collect their epidemiological, demographic, laboratory, and clinical information and treatment outcome. Results. In all, 930 electronic medical records of the hospitalized patients (351 in the third wave and 579 in the fourth wave) were studied. In the third and fourth waves, 29.06% and 13.13% of the patients had severe COVID-19, respectively (P = 0.001). The number of deaths in the third wave was larger compared to the fourth wave (P = 0.015). The mean duration of hospitalization was longer in the third wave than in the fourth wave (P = 0.001). The drugs administered most in these two waves were remdesivir, dexamethasone, and heparin, and the patients who received these drugs were compared in the third and fourth waves (P = 0.001). Conclusion. The reduced rate of mortality in the fourth wave was compared to the third wave. This reduction can be attributed to the change in the national strategy adopted in terms of hospitalization criteria and treatment protocols taking into account the acquired experience, earlier hospitalization, and start of drug therapy.http://dx.doi.org/10.1155/2022/9634241 |
| spellingShingle | Samira Eshghinia Rahmat Allah Sharifi Far Naghimeh Hajimoradloo Ali Sinesepehr Ahmad Sohrsbi Mousa Imeri Amir Reza Khodanazar Kalti Erfan Rezaie Shirazi Roghieh Golsha The Comparison of Clinical Epidemiology of Hospitalized Patients with COVID-19 during the Third and Fourth Waves of the Pandemic in Gorgan Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | The Comparison of Clinical Epidemiology of Hospitalized Patients with COVID-19 during the Third and Fourth Waves of the Pandemic in Gorgan |
| title_full | The Comparison of Clinical Epidemiology of Hospitalized Patients with COVID-19 during the Third and Fourth Waves of the Pandemic in Gorgan |
| title_fullStr | The Comparison of Clinical Epidemiology of Hospitalized Patients with COVID-19 during the Third and Fourth Waves of the Pandemic in Gorgan |
| title_full_unstemmed | The Comparison of Clinical Epidemiology of Hospitalized Patients with COVID-19 during the Third and Fourth Waves of the Pandemic in Gorgan |
| title_short | The Comparison of Clinical Epidemiology of Hospitalized Patients with COVID-19 during the Third and Fourth Waves of the Pandemic in Gorgan |
| title_sort | comparison of clinical epidemiology of hospitalized patients with covid 19 during the third and fourth waves of the pandemic in gorgan |
| url | http://dx.doi.org/10.1155/2022/9634241 |
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