Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing

Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing

Abstract The scar-free healing remains a clinical challenge, and requires the concerted efforts of multiple cell types, such as keratinocytes and fibroblasts. Exosomes derived from human adipose-derived mesenchymal stem cells (hADSC-Exos) have emerged as a promising therapeutic option. Nonetheless,...

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Bibliographic Details
Main Authors: Yu Fu, Jun-ling Xie, Xing-liao Zhang, Guang-ming Xie, Xin-Min Zhang, Yao-ting Han, Meng-meng Xu, Jing Zhang, Jun Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Nanobiotechnology
Online Access:https://doi.org/10.1186/s12951-025-03548-y
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