SCA 15 presenting with parkinsonism–dystonia, tremor, and psychosis in an Indian woman

Spinocerebellar ataxias (SCAs) represent a diverse group of hereditary and progressive neurological disorders characterized by their onset in adulthood and commonly exhibit autosomal dominant inheritance. These disorders typically involve multiple brain regions, including the cerebellum, spinal cord...

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Main Authors: Narendrakumar H. Barad, Charulata Sankhla
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-05-01
Series:Annals of Movement Disorders
Subjects:
Online Access:https://doi.org/10.4103/aomd.aomd_32_23
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author Narendrakumar H. Barad
Charulata Sankhla
author_facet Narendrakumar H. Barad
Charulata Sankhla
author_sort Narendrakumar H. Barad
collection DOAJ
description Spinocerebellar ataxias (SCAs) represent a diverse group of hereditary and progressive neurological disorders characterized by their onset in adulthood and commonly exhibit autosomal dominant inheritance. These disorders typically involve multiple brain regions, including the cerebellum, spinal cord, basal ganglia, brainstem, and cortical areas, leading to varied and heterogeneous clinical presentations. In particular, SCA 15 is recognized as an adult-onset, slowly progressive cerebellar syndrome, often accompanied by various other neurological manifestations. In this report, we present a novel clinical phenotype of parkinsonism–dystonia syndrome co-occurring with cerebellar features in a genetically confirmed case of SCA 15.
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publisher Wolters Kluwer Medknow Publications
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series Annals of Movement Disorders
spelling doaj-art-54454d63c8714749a200c8f52d79b72b2025-08-20T02:46:36ZengWolters Kluwer Medknow PublicationsAnnals of Movement Disorders2590-34462590-34542024-05-017211211510.4103/aomd.aomd_32_23SCA 15 presenting with parkinsonism–dystonia, tremor, and psychosis in an Indian womanNarendrakumar H. BaradCharulata SankhlaSpinocerebellar ataxias (SCAs) represent a diverse group of hereditary and progressive neurological disorders characterized by their onset in adulthood and commonly exhibit autosomal dominant inheritance. These disorders typically involve multiple brain regions, including the cerebellum, spinal cord, basal ganglia, brainstem, and cortical areas, leading to varied and heterogeneous clinical presentations. In particular, SCA 15 is recognized as an adult-onset, slowly progressive cerebellar syndrome, often accompanied by various other neurological manifestations. In this report, we present a novel clinical phenotype of parkinsonism–dystonia syndrome co-occurring with cerebellar features in a genetically confirmed case of SCA 15.https://doi.org/10.4103/aomd.aomd_32_23dystoniaparkinsonismpsychosissca 15spinocerebellar ataxias
spellingShingle Narendrakumar H. Barad
Charulata Sankhla
SCA 15 presenting with parkinsonism–dystonia, tremor, and psychosis in an Indian woman
Annals of Movement Disorders
dystonia
parkinsonism
psychosis
sca 15
spinocerebellar ataxias
title SCA 15 presenting with parkinsonism–dystonia, tremor, and psychosis in an Indian woman
title_full SCA 15 presenting with parkinsonism–dystonia, tremor, and psychosis in an Indian woman
title_fullStr SCA 15 presenting with parkinsonism–dystonia, tremor, and psychosis in an Indian woman
title_full_unstemmed SCA 15 presenting with parkinsonism–dystonia, tremor, and psychosis in an Indian woman
title_short SCA 15 presenting with parkinsonism–dystonia, tremor, and psychosis in an Indian woman
title_sort sca 15 presenting with parkinsonism dystonia tremor and psychosis in an indian woman
topic dystonia
parkinsonism
psychosis
sca 15
spinocerebellar ataxias
url https://doi.org/10.4103/aomd.aomd_32_23
work_keys_str_mv AT narendrakumarhbarad sca15presentingwithparkinsonismdystoniatremorandpsychosisinanindianwoman
AT charulatasankhla sca15presentingwithparkinsonismdystoniatremorandpsychosisinanindianwoman