Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata

Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata

BackgroundAlopecia areata (AA) is a common autoimmune disorder marked by non-scarring hair loss, which imposes significant psychosocial stress on patients. To investigate key metabolites and ions involved in AA’s pathogenesis, we utilized gas chromatography-mass spectrometry (GC-MS) for non-targeted...

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Bibliographic Details
Main Authors: Luning Li, Zhen Sun, Wenxue Sun, Yujuan Zhai, Na Ding, Wei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
gas chromatography-mass spectrometry
metabolome
inductively coupled plasma mass spectrometry
ionome
alopecia areata
tofacitinib
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1507348/full
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