Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases

Myeloid-derived suppressor cells are immature myeloid cells with immunosuppressive properties. The review presents characteristics of myeloid-derived suppressor cells. It includes phenotype variants, mechanisms of the suppressive effect on the immune system, and tumor recruitment mechanisms of myelo...

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Main Author: AV Ponomarev
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2017-01-01
Series:Клиническая онкогематология
Subjects:
Online Access:http://bloodjournal.ru/wp-content/uploads/2017/01/4-1.pdf
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author AV Ponomarev
author_facet AV Ponomarev
author_sort AV Ponomarev
collection DOAJ
description Myeloid-derived suppressor cells are immature myeloid cells with immunosuppressive properties. The review presents characteristics of myeloid-derived suppressor cells. It includes phenotype variants, mechanisms of the suppressive effect on the immune system, and tumor recruitment mechanisms of myeloid suppressors. It provides a brief description of works which studied myeloid suppressor in oncohematological diseases including multiple myeloma, lymphomas, and leukemias.
format Article
id doaj-art-5432882c49bf4a6abccd1df438b656a4
institution OA Journals
issn 1997-6933
2500-2139
language Russian
publishDate 2017-01-01
publisher Practical Medicine Publishing House
record_format Article
series Клиническая онкогематология
spelling doaj-art-5432882c49bf4a6abccd1df438b656a42025-08-20T01:57:20ZrusPractical Medicine Publishing HouseКлиническая онкогематология1997-69332500-21392017-01-01101293810.21320/2500-2139-2017-10-1-29-38Myeloid-Derived Suppressor Cells in Some Oncohematological DiseasesAV Ponomarev0NN Blokhin Russian Cancer Research Center, 24 Kashirskoye sh., Moscow, Russian Federation, 115478Myeloid-derived suppressor cells are immature myeloid cells with immunosuppressive properties. The review presents characteristics of myeloid-derived suppressor cells. It includes phenotype variants, mechanisms of the suppressive effect on the immune system, and tumor recruitment mechanisms of myeloid suppressors. It provides a brief description of works which studied myeloid suppressor in oncohematological diseases including multiple myeloma, lymphomas, and leukemias.http://bloodjournal.ru/wp-content/uploads/2017/01/4-1.pdfmyeloid suppressorsmyeloid-derived suppressor cellsmultiple myelomalymphomasleukemias
spellingShingle AV Ponomarev
Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
Клиническая онкогематология
myeloid suppressors
myeloid-derived suppressor cells
multiple myeloma
lymphomas
leukemias
title Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
title_full Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
title_fullStr Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
title_full_unstemmed Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
title_short Myeloid-Derived Suppressor Cells in Some Oncohematological Diseases
title_sort myeloid derived suppressor cells in some oncohematological diseases
topic myeloid suppressors
myeloid-derived suppressor cells
multiple myeloma
lymphomas
leukemias
url http://bloodjournal.ru/wp-content/uploads/2017/01/4-1.pdf
work_keys_str_mv AT avponomarev myeloidderivedsuppressorcellsinsomeoncohematologicaldiseases