Recurrence of pulmonary tuberculosis in India: Findings from the 2019-2021 nationwide community-based TB prevalence survey.

Recurrent Tuberculosis patients contribute to a significant proportion of TB burden in India. A nationwide survey was conducted during 2019-2021 across India among adults to estimate the prevalence of TB. A total of 322480 individuals were screened and 1402 were having TB. Of this, 381 (27.1%) had r...

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Main Authors: Prathiksha Giridharan, Sriram Selvaraju, Raghuram Rao, Kiran Rade, Kannan Thiruvengadam, Smita Asthana, Rakesh Balachandar, Sampada Dipak Bangar, Avi Kumar Bansal, Jyothi Bhat, Debjit Chakraborty, Vishal Chopra, Dasarathi Das, Shanta Dutta, Kangjam Rekha Devi, Sunil Kumar, Avula Laxmaiah, Major Madhukar, Amarendra Mahapatra, Suman Sundar Mohanty, Chethana Rangaraju, Jyotirmayee Turuk, Kamran Zaman, Rajendran Krishnan, Sivakumar Shanmugam, Nishant Kumar, Rajendra Panduranga Joshi, Somashekar Narasimhaiah, Padmapriyadarsini Chandrasekaran, Raman R Gangakhedkar, Balram Bhargava
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0294254&type=printable
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author Prathiksha Giridharan
Sriram Selvaraju
Raghuram Rao
Kiran Rade
Kannan Thiruvengadam
Smita Asthana
Rakesh Balachandar
Sampada Dipak Bangar
Avi Kumar Bansal
Jyothi Bhat
Debjit Chakraborty
Vishal Chopra
Dasarathi Das
Shanta Dutta
Kangjam Rekha Devi
Sunil Kumar
Avula Laxmaiah
Major Madhukar
Amarendra Mahapatra
Suman Sundar Mohanty
Chethana Rangaraju
Jyotirmayee Turuk
Kamran Zaman
Rajendran Krishnan
Sivakumar Shanmugam
Nishant Kumar
Rajendra Panduranga Joshi
Somashekar Narasimhaiah
Padmapriyadarsini Chandrasekaran
Raman R Gangakhedkar
Balram Bhargava
author_facet Prathiksha Giridharan
Sriram Selvaraju
Raghuram Rao
Kiran Rade
Kannan Thiruvengadam
Smita Asthana
Rakesh Balachandar
Sampada Dipak Bangar
Avi Kumar Bansal
Jyothi Bhat
Debjit Chakraborty
Vishal Chopra
Dasarathi Das
Shanta Dutta
Kangjam Rekha Devi
Sunil Kumar
Avula Laxmaiah
Major Madhukar
Amarendra Mahapatra
Suman Sundar Mohanty
Chethana Rangaraju
Jyotirmayee Turuk
Kamran Zaman
Rajendran Krishnan
Sivakumar Shanmugam
Nishant Kumar
Rajendra Panduranga Joshi
Somashekar Narasimhaiah
Padmapriyadarsini Chandrasekaran
Raman R Gangakhedkar
Balram Bhargava
author_sort Prathiksha Giridharan
collection DOAJ
description Recurrent Tuberculosis patients contribute to a significant proportion of TB burden in India. A nationwide survey was conducted during 2019-2021 across India among adults to estimate the prevalence of TB. A total of 322480 individuals were screened and 1402 were having TB. Of this, 381 (27.1%) had recurrent TB. The crude prevalence (95% CI) of recurrent TB was 118 (107-131) per 100,000 population. The median duration between episodes of TB was 24 months. The proportion of drug resistant TB was 11.3% and 3.6% in the recurrent group and new TB patients respectively. Higher prevalence of recurrent TB was observed in elderly, males, malnourished, known diabetics, smokers, and alcohol users. (p<0.001). To prevent TB recurrence, all treated tuberculosis patients must be followed at least for 24 months, with screening for Chest X-ray, liquid culture every 6 months, smoking cessation, alcohol cessation, nutritional interventions and good diabetic management.
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spelling doaj-art-542ebb64d0874fc2b7eccf9322a3b6712025-08-20T03:44:38ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-011812e029425410.1371/journal.pone.0294254Recurrence of pulmonary tuberculosis in India: Findings from the 2019-2021 nationwide community-based TB prevalence survey.Prathiksha GiridharanSriram SelvarajuRaghuram RaoKiran RadeKannan ThiruvengadamSmita AsthanaRakesh BalachandarSampada Dipak BangarAvi Kumar BansalJyothi BhatDebjit ChakrabortyVishal ChopraDasarathi DasShanta DuttaKangjam Rekha DeviSunil KumarAvula LaxmaiahMajor MadhukarAmarendra MahapatraSuman Sundar MohantyChethana RangarajuJyotirmayee TurukKamran ZamanRajendran KrishnanSivakumar ShanmugamNishant KumarRajendra Panduranga JoshiSomashekar NarasimhaiahPadmapriyadarsini ChandrasekaranRaman R GangakhedkarBalram BhargavaRecurrent Tuberculosis patients contribute to a significant proportion of TB burden in India. A nationwide survey was conducted during 2019-2021 across India among adults to estimate the prevalence of TB. A total of 322480 individuals were screened and 1402 were having TB. Of this, 381 (27.1%) had recurrent TB. The crude prevalence (95% CI) of recurrent TB was 118 (107-131) per 100,000 population. The median duration between episodes of TB was 24 months. The proportion of drug resistant TB was 11.3% and 3.6% in the recurrent group and new TB patients respectively. Higher prevalence of recurrent TB was observed in elderly, males, malnourished, known diabetics, smokers, and alcohol users. (p<0.001). To prevent TB recurrence, all treated tuberculosis patients must be followed at least for 24 months, with screening for Chest X-ray, liquid culture every 6 months, smoking cessation, alcohol cessation, nutritional interventions and good diabetic management.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0294254&type=printable
spellingShingle Prathiksha Giridharan
Sriram Selvaraju
Raghuram Rao
Kiran Rade
Kannan Thiruvengadam
Smita Asthana
Rakesh Balachandar
Sampada Dipak Bangar
Avi Kumar Bansal
Jyothi Bhat
Debjit Chakraborty
Vishal Chopra
Dasarathi Das
Shanta Dutta
Kangjam Rekha Devi
Sunil Kumar
Avula Laxmaiah
Major Madhukar
Amarendra Mahapatra
Suman Sundar Mohanty
Chethana Rangaraju
Jyotirmayee Turuk
Kamran Zaman
Rajendran Krishnan
Sivakumar Shanmugam
Nishant Kumar
Rajendra Panduranga Joshi
Somashekar Narasimhaiah
Padmapriyadarsini Chandrasekaran
Raman R Gangakhedkar
Balram Bhargava
Recurrence of pulmonary tuberculosis in India: Findings from the 2019-2021 nationwide community-based TB prevalence survey.
PLoS ONE
title Recurrence of pulmonary tuberculosis in India: Findings from the 2019-2021 nationwide community-based TB prevalence survey.
title_full Recurrence of pulmonary tuberculosis in India: Findings from the 2019-2021 nationwide community-based TB prevalence survey.
title_fullStr Recurrence of pulmonary tuberculosis in India: Findings from the 2019-2021 nationwide community-based TB prevalence survey.
title_full_unstemmed Recurrence of pulmonary tuberculosis in India: Findings from the 2019-2021 nationwide community-based TB prevalence survey.
title_short Recurrence of pulmonary tuberculosis in India: Findings from the 2019-2021 nationwide community-based TB prevalence survey.
title_sort recurrence of pulmonary tuberculosis in india findings from the 2019 2021 nationwide community based tb prevalence survey
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0294254&type=printable
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