Next‐Generation HER‐2 Tumor‐Targeted Delivery of the STING Agonist Immune‐Stimulating Antibody Conjugate (ISAC) Improves Anticancer Efficacy and Induces Immunological Memory
ABSTRACT Recently, rapidly evolving STING‐based immunotherapies have offered novel therapeutic options for various cancer types. However, systemic administration of STING agonists raises safety concerns, and intratumoral injection is constrained by tumor accessibility. Herein we developed an immune‐...
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| Main Authors: | Gang Wu, Chuanfei Yu, Chunyong Ding, Shengtao Yao, Jialiang Du, Zhihao Fu, Yu Liu, Yiming Fan, Guanghao Wu, Ao Zhang, Junzhi Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-07-01
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| Series: | MedComm |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/mco2.70254 |
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