Genome-wide association study of pulpal and apical diseases

Genome-wide association study of pulpal and apical diseases

Abstract Infections of the dental pulp are common sequelae of microbial activity and host susceptibility, affecting >80% of adult population. We performed a genome-wide association study on endodontic infections utilizing Finnish health registry and genotype data from FinnGen. Cases [132,124 (27....

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Main Authors: Aino Salminen, Kati Hyvärinen, Jarmo Ritari, Jussi M. Leppilahti, Ulla Palotie, Ville Vuollo, Oleg Kambur, FinnGen, Estonian Biobank Research Team, Kadri Reis, Anu Reigo, Priit Palta, Markus Perola, Juha Sinisalo, Aki S. Havulinna, Päivi Mäntylä, Ulvi Kahraman Gürsoy, A. Liisa Suominen, David P. Rice, Vuokko Anttonen, Pekka Nieminen, Pirkko J. Pussinen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61721-1
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