Investigation of Systemic Immune Inflammatory Index and Prognostic Nutritional Index in Prediction of Major Adverse Cardiovascular and Cerebral Events Occurring After Coronary Artery Bypass Operations
Aim: The most valuable treatment method for coronary artery disease is coronary artery bypass graft (CABG) surgery. Major cardiovascular and cerebral events (MACCE) are important challenges, and it is particularly important to reveal possible risk factors in this regard. In this study, we aimed to i...
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Alanya Alaaddin Keykubat University
2021-12-01
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| Series: | Acta Medica Alanya |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/1737392 |
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| author | Mesut Engin Mustafa Abanoz |
| author_facet | Mesut Engin Mustafa Abanoz |
| author_sort | Mesut Engin |
| collection | DOAJ |
| description | Aim: The most valuable treatment method for coronary artery disease is coronary artery bypass graft (CABG) surgery. Major cardiovascular and cerebral events (MACCE) are important challenges, and it is particularly important to reveal possible risk factors in this regard. In this study, we aimed to investigate the predictive areas of the prognostic nutritional index (PNI) and the systemic immune inflammation index (SII) on early postoperatively developing MACCE, in patients who underwent isolated CABG operationMethods: The patients between the ages of 20 and 85 years who underwent consecutive isolated CABG operation in our clinic between May 15th, 2016, and May 15th, 2020, were included in the study retrospectively. In the postoperative period (within a month), those who did not develop MACCE were recorded as Group 1, and those who developed MACCE as Group 2.Results: A total of 297 consecutive patients were included in the study. Group 1 had 263 patients with a median age of 63 (32-80), Group 2 had 34 patients with a median age of 70 (36-85) (P=0.008). There was no difference between the groups in terms of gender, history of cerebrovascular events, smoking, body mass index, hyperlipidemia, ejection fraction, and chronic obstructive pulmonary disease rates. As a result of multivariate analysis, advanced age (OR: 1.230 CI 95%: 1.050-1.319 P=0.024), NLR (OR: 1.974 CI 95%: 1.614-3.120, P=0.009), SII (OR: 3.880, CI 95%: 2.690-6.150, P<0.001) and PNI (OR: 2.424, CI 95%: 1.880-3.880, P=0.002) values were determined as independent predictors for predicting early postoperative MACCE.Conclusion: With this study we revealed that SII and PNI values, which are among the inflammatory parameters and which can be obtained cheaply and easily, may be good predictors for MACCE emerging after CABG operations. |
| format | Article |
| id | doaj-art-541f9727a30e4e869e0342b89d43c3f9 |
| institution | Kabale University |
| issn | 2587-0319 |
| language | English |
| publishDate | 2021-12-01 |
| publisher | Alanya Alaaddin Keykubat University |
| record_format | Article |
| series | Acta Medica Alanya |
| spelling | doaj-art-541f9727a30e4e869e0342b89d43c3f92025-08-20T03:53:22ZengAlanya Alaaddin Keykubat UniversityActa Medica Alanya2587-03192021-12-015326326910.30565/medalanya.929006727Investigation of Systemic Immune Inflammatory Index and Prognostic Nutritional Index in Prediction of Major Adverse Cardiovascular and Cerebral Events Occurring After Coronary Artery Bypass OperationsMesut Engin0https://orcid.org/0000-0003-2418-5823Mustafa Abanoz1https://orcid.org/0000-0003-1821-1706SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, BURSA YÜKSEK İHTİSAS SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, KALP VE DAMAR CERRAHİSİ ANABİLİM DALIUNIVERSITY OF HEALTH SCIENCES, ŞANLIURFA MEHMET AKİF İNAN HEALTH RESEARCH CENTERAim: The most valuable treatment method for coronary artery disease is coronary artery bypass graft (CABG) surgery. Major cardiovascular and cerebral events (MACCE) are important challenges, and it is particularly important to reveal possible risk factors in this regard. In this study, we aimed to investigate the predictive areas of the prognostic nutritional index (PNI) and the systemic immune inflammation index (SII) on early postoperatively developing MACCE, in patients who underwent isolated CABG operationMethods: The patients between the ages of 20 and 85 years who underwent consecutive isolated CABG operation in our clinic between May 15th, 2016, and May 15th, 2020, were included in the study retrospectively. In the postoperative period (within a month), those who did not develop MACCE were recorded as Group 1, and those who developed MACCE as Group 2.Results: A total of 297 consecutive patients were included in the study. Group 1 had 263 patients with a median age of 63 (32-80), Group 2 had 34 patients with a median age of 70 (36-85) (P=0.008). There was no difference between the groups in terms of gender, history of cerebrovascular events, smoking, body mass index, hyperlipidemia, ejection fraction, and chronic obstructive pulmonary disease rates. As a result of multivariate analysis, advanced age (OR: 1.230 CI 95%: 1.050-1.319 P=0.024), NLR (OR: 1.974 CI 95%: 1.614-3.120, P=0.009), SII (OR: 3.880, CI 95%: 2.690-6.150, P<0.001) and PNI (OR: 2.424, CI 95%: 1.880-3.880, P=0.002) values were determined as independent predictors for predicting early postoperative MACCE.Conclusion: With this study we revealed that SII and PNI values, which are among the inflammatory parameters and which can be obtained cheaply and easily, may be good predictors for MACCE emerging after CABG operations.https://dergipark.org.tr/tr/download/article-file/1737392coronary artery bypass graftinginflammationnutritional indexpostoperative complicationkoroner arter baypas grefti̇nflamasyonnutrisyonel indekspostoperatif komplikasyon |
| spellingShingle | Mesut Engin Mustafa Abanoz Investigation of Systemic Immune Inflammatory Index and Prognostic Nutritional Index in Prediction of Major Adverse Cardiovascular and Cerebral Events Occurring After Coronary Artery Bypass Operations Acta Medica Alanya coronary artery bypass grafting inflammation nutritional index postoperative complication koroner arter baypas greft i̇nflamasyon nutrisyonel indeks postoperatif komplikasyon |
| title | Investigation of Systemic Immune Inflammatory Index and Prognostic Nutritional Index in Prediction of Major Adverse Cardiovascular and Cerebral Events Occurring After Coronary Artery Bypass Operations |
| title_full | Investigation of Systemic Immune Inflammatory Index and Prognostic Nutritional Index in Prediction of Major Adverse Cardiovascular and Cerebral Events Occurring After Coronary Artery Bypass Operations |
| title_fullStr | Investigation of Systemic Immune Inflammatory Index and Prognostic Nutritional Index in Prediction of Major Adverse Cardiovascular and Cerebral Events Occurring After Coronary Artery Bypass Operations |
| title_full_unstemmed | Investigation of Systemic Immune Inflammatory Index and Prognostic Nutritional Index in Prediction of Major Adverse Cardiovascular and Cerebral Events Occurring After Coronary Artery Bypass Operations |
| title_short | Investigation of Systemic Immune Inflammatory Index and Prognostic Nutritional Index in Prediction of Major Adverse Cardiovascular and Cerebral Events Occurring After Coronary Artery Bypass Operations |
| title_sort | investigation of systemic immune inflammatory index and prognostic nutritional index in prediction of major adverse cardiovascular and cerebral events occurring after coronary artery bypass operations |
| topic | coronary artery bypass grafting inflammation nutritional index postoperative complication koroner arter baypas greft i̇nflamasyon nutrisyonel indeks postoperatif komplikasyon |
| url | https://dergipark.org.tr/tr/download/article-file/1737392 |
| work_keys_str_mv | AT mesutengin investigationofsystemicimmuneinflammatoryindexandprognosticnutritionalindexinpredictionofmajoradversecardiovascularandcerebraleventsoccurringaftercoronaryarterybypassoperations AT mustafaabanoz investigationofsystemicimmuneinflammatoryindexandprognosticnutritionalindexinpredictionofmajoradversecardiovascularandcerebraleventsoccurringaftercoronaryarterybypassoperations |