Saline nebulizers in treatment of bronchiolitis
Introduction: This study was conducted to assess the response to treatment and compare the effects of nebulized normal saline 0.9% and hypertonic saline 3% in the management of acute bronchiolitis, a condition associated with multiple complications in pediatric patients. Materials and Methods: In th...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jfmpc.jfmpc_244_24 |
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| _version_ | 1850263919029911552 |
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| author | Seyedeh Mahsa Mahmoudinezhad Dezfouli Saeid Gholami Gharab Reza Hamidi Mansour Mahmoodi Manizhe Nasirizade Roya Ghafoury Samane Sadat Khoobbin Khoshnazar |
| author_facet | Seyedeh Mahsa Mahmoudinezhad Dezfouli Saeid Gholami Gharab Reza Hamidi Mansour Mahmoodi Manizhe Nasirizade Roya Ghafoury Samane Sadat Khoobbin Khoshnazar |
| author_sort | Seyedeh Mahsa Mahmoudinezhad Dezfouli |
| collection | DOAJ |
| description | Introduction:
This study was conducted to assess the response to treatment and compare the effects of nebulized normal saline 0.9% and hypertonic saline 3% in the management of acute bronchiolitis, a condition associated with multiple complications in pediatric patients.
Materials and Methods:
In this clinical trial, a total of 60 children diagnosed with viral bronchiolitis in the autumn and winter of 2018 at Ali Asghar Children’s Hospital’s emergency department were enrolled. The cohort consisted of 30 children in the control group treated with normal saline 0.9% nebulization and 30 in the treatment group treated with 3% hypertonic saline nebulization. Demographic variables, symptom onset duration, and initial heart and respiratory rates were recorded. Disease severity was assessed using the Respiratory Distress Assessment Index (RDAI). Data were analyzed using SPSS software.
Results:
Following treatment, both groups exhibited significant improvements in vital signs (respiratory rate, heart rate, and oxygen saturation) and RDAI scores (P value < 0.001). However, there was no statistically significant difference in the degree of improvement in vital signs and RDAI scores between the two treatment groups (P value > 0.05). The mean hospital stay duration did not significantly differ between the groups (P value = 0.16).
Conclusion:
Nebulized hypertonic saline and normal saline both effectively ameliorated symptoms in children with bronchiolitis. The absence of a significant difference between these treatments suggests that either can be recommended for use in the pediatric population experiencing acute bronchiolitis symptoms. |
| format | Article |
| id | doaj-art-540deaddfafb4c4bb1fa14b8a70a0af4 |
| institution | OA Journals |
| issn | 2249-4863 2278-7135 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj-art-540deaddfafb4c4bb1fa14b8a70a0af42025-08-20T01:54:50ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352024-11-0113114937494210.4103/jfmpc.jfmpc_244_24Saline nebulizers in treatment of bronchiolitisSeyedeh Mahsa Mahmoudinezhad DezfouliSaeid Gholami GharabReza HamidiMansour MahmoodiManizhe NasirizadeRoya GhafourySamane Sadat Khoobbin KhoshnazarIntroduction: This study was conducted to assess the response to treatment and compare the effects of nebulized normal saline 0.9% and hypertonic saline 3% in the management of acute bronchiolitis, a condition associated with multiple complications in pediatric patients. Materials and Methods: In this clinical trial, a total of 60 children diagnosed with viral bronchiolitis in the autumn and winter of 2018 at Ali Asghar Children’s Hospital’s emergency department were enrolled. The cohort consisted of 30 children in the control group treated with normal saline 0.9% nebulization and 30 in the treatment group treated with 3% hypertonic saline nebulization. Demographic variables, symptom onset duration, and initial heart and respiratory rates were recorded. Disease severity was assessed using the Respiratory Distress Assessment Index (RDAI). Data were analyzed using SPSS software. Results: Following treatment, both groups exhibited significant improvements in vital signs (respiratory rate, heart rate, and oxygen saturation) and RDAI scores (P value < 0.001). However, there was no statistically significant difference in the degree of improvement in vital signs and RDAI scores between the two treatment groups (P value > 0.05). The mean hospital stay duration did not significantly differ between the groups (P value = 0.16). Conclusion: Nebulized hypertonic saline and normal saline both effectively ameliorated symptoms in children with bronchiolitis. The absence of a significant difference between these treatments suggests that either can be recommended for use in the pediatric population experiencing acute bronchiolitis symptoms.https://journals.lww.com/10.4103/jfmpc.jfmpc_244_24bronchiolitishypertonic saline 3%normal saline 0.9% |
| spellingShingle | Seyedeh Mahsa Mahmoudinezhad Dezfouli Saeid Gholami Gharab Reza Hamidi Mansour Mahmoodi Manizhe Nasirizade Roya Ghafoury Samane Sadat Khoobbin Khoshnazar Saline nebulizers in treatment of bronchiolitis Journal of Family Medicine and Primary Care bronchiolitis hypertonic saline 3% normal saline 0.9% |
| title | Saline nebulizers in treatment of bronchiolitis |
| title_full | Saline nebulizers in treatment of bronchiolitis |
| title_fullStr | Saline nebulizers in treatment of bronchiolitis |
| title_full_unstemmed | Saline nebulizers in treatment of bronchiolitis |
| title_short | Saline nebulizers in treatment of bronchiolitis |
| title_sort | saline nebulizers in treatment of bronchiolitis |
| topic | bronchiolitis hypertonic saline 3% normal saline 0.9% |
| url | https://journals.lww.com/10.4103/jfmpc.jfmpc_244_24 |
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