Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific Antigen

A man with prostate cancer on a regime of active surveillance had a laboratory-confirmed acute Chikungunya virus infection. The patient experienced a sudden increase in serum Prostate-Specific Antigen (PSA) during the acute illness that caused him anxiety and confounded interpretation of the PSA tes...

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Main Authors: William Derval Aiken, Joshua J. Anzinger
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2015/120535
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author William Derval Aiken
Joshua J. Anzinger
author_facet William Derval Aiken
Joshua J. Anzinger
author_sort William Derval Aiken
collection DOAJ
description A man with prostate cancer on a regime of active surveillance had a laboratory-confirmed acute Chikungunya virus infection. The patient experienced a sudden increase in serum Prostate-Specific Antigen (PSA) during the acute illness that caused him anxiety and confounded interpretation of the PSA test. Six weeks after the onset of Chikungunya Fever symptoms, the elevated serum PSA returned to baseline. The association of Chikungunya Fever and elevated serum PSA may result in misinterpretation of the PSA test, triggering unnecessary prostate biopsy or other management errors.
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spelling doaj-art-540da208324242548eb8ff12fc4931602025-02-03T01:12:31ZengWileyCase Reports in Urology2090-696X2090-69782015-01-01201510.1155/2015/120535120535Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific AntigenWilliam Derval Aiken0Joshua J. Anzinger1Division of Urology, Section of Surgery, Department of Surgery, Anaesthesia & Intensive Care and Emergency Medicine, Faculty of Medical Sciences, University of the West Indies, Mona, Kingston 7, JamaicaDepartment of Microbiology, Faculty of Medical Sciences, University of the West Indies, Mona, Kingston 7, JamaicaA man with prostate cancer on a regime of active surveillance had a laboratory-confirmed acute Chikungunya virus infection. The patient experienced a sudden increase in serum Prostate-Specific Antigen (PSA) during the acute illness that caused him anxiety and confounded interpretation of the PSA test. Six weeks after the onset of Chikungunya Fever symptoms, the elevated serum PSA returned to baseline. The association of Chikungunya Fever and elevated serum PSA may result in misinterpretation of the PSA test, triggering unnecessary prostate biopsy or other management errors.http://dx.doi.org/10.1155/2015/120535
spellingShingle William Derval Aiken
Joshua J. Anzinger
Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific Antigen
Case Reports in Urology
title Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific Antigen
title_full Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific Antigen
title_fullStr Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific Antigen
title_full_unstemmed Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific Antigen
title_short Chikungunya Virus Infection and Acute Elevation of Serum Prostate-Specific Antigen
title_sort chikungunya virus infection and acute elevation of serum prostate specific antigen
url http://dx.doi.org/10.1155/2015/120535
work_keys_str_mv AT williamdervalaiken chikungunyavirusinfectionandacuteelevationofserumprostatespecificantigen
AT joshuajanzinger chikungunyavirusinfectionandacuteelevationofserumprostatespecificantigen