Conducting a real-world study of Tumor Necrosis factor-alpha inhibitors-induced Systemic Lupus Erythematosus based on the FAERS database

Conducting a real-world study of Tumor Necrosis factor-alpha inhibitors-induced Systemic Lupus Erythematosus based on the FAERS database

Abstract This study characterized the risk and characteristics of tumor necrosis factor-α (TNF-α) inhibitors-induced systemic lupus erythematosus (SLE) in a mass medication population based on the FAERS database. Using the Standardized MedDRA Query (SMQ), adverse drug reaction (ADR) reports related...

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Bibliographic Details
Main Authors: Mengjiao He, Jiale Yang, Simin Yan, Qing Shu, Peng Cheng Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Systemic lupus erythematosus
FAERS database
Disproportionality analysis;
Pharmacovigilance
Online Access:https://doi.org/10.1038/s41598-025-90566-3
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