Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature

Introduction. Reactive lymphoid hyperplasia (RLH) is a rare and benign lesion found in organs of the gastrointestinal tract, skin, lung, orbit, and more rarely in the liver. Due to its similar appearance on imaging, it is hard to differentiate from primary liver malignancies. The following is a case...

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Main Authors: Samantha Seitter, Zachary D. Goodman, Theodore M. Friedman, Timothy R. Shaver, George Younan
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2018/9264251
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author Samantha Seitter
Zachary D. Goodman
Theodore M. Friedman
Timothy R. Shaver
George Younan
author_facet Samantha Seitter
Zachary D. Goodman
Theodore M. Friedman
Timothy R. Shaver
George Younan
author_sort Samantha Seitter
collection DOAJ
description Introduction. Reactive lymphoid hyperplasia (RLH) is a rare and benign lesion found in organs of the gastrointestinal tract, skin, lung, orbit, and more rarely in the liver. Due to its similar appearance on imaging, it is hard to differentiate from primary liver malignancies. The following is a case report of a patient presenting with a suspicious liver lesion found to be RLH associated with primary biliary cirrhosis (PBC), after surgical resection. Presentation of Case. A 54-year-old woman presented with nonspecific abdominal pain, and her workup included axial imaging of the abdomen that showed a suspicious lesion in her liver. After an extensive workup, which included a percutaneous biopsy, failed to confirm a diagnosis, a laparoscopic surgical resection was recommended. Discussion. RLH is a rare condition of the liver, presenting in a suspicious fashion and raising concerns for a primary liver malignancy. RLH should be considered in the differential diagnosis of small hepatic lesions in middle-age females in the absence of any significant risk factors for hepatocellular carcinoma (HCC). RLH tends to be associated with PBC of the liver. Conclusion. RLH of the liver is a rare, hard to diagnose, benign lesion. When intrahepatic, it cannot be easily differentiated from primary liver tumors and frequently requires surgical resection for pathological diagnostic confirmation.
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spelling doaj-art-53fd77b36e244b9b814feeeaf913ff422025-08-20T03:36:25ZengWileyCase Reports in Surgery2090-69002090-69192018-01-01201810.1155/2018/92642519264251Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the LiteratureSamantha Seitter0Zachary D. Goodman1Theodore M. Friedman2Timothy R. Shaver3George Younan4Department of Surgery, Inova Fairfax Hospital, Fairfax, VA, USADepartment of Pathology, Inova Fairfax Hospital, Fairfax, VA, USADepartment of Pathology, Inova Fair Oaks Hospital, Fairfax, VA, USADivision of Hepato-Pancreato-Biliary Surgery, Virginia Surgery Associates, Fairfax, VA, USADivision of Hepato-Pancreato-Biliary Surgery, Virginia Surgery Associates, Fairfax, VA, USAIntroduction. Reactive lymphoid hyperplasia (RLH) is a rare and benign lesion found in organs of the gastrointestinal tract, skin, lung, orbit, and more rarely in the liver. Due to its similar appearance on imaging, it is hard to differentiate from primary liver malignancies. The following is a case report of a patient presenting with a suspicious liver lesion found to be RLH associated with primary biliary cirrhosis (PBC), after surgical resection. Presentation of Case. A 54-year-old woman presented with nonspecific abdominal pain, and her workup included axial imaging of the abdomen that showed a suspicious lesion in her liver. After an extensive workup, which included a percutaneous biopsy, failed to confirm a diagnosis, a laparoscopic surgical resection was recommended. Discussion. RLH is a rare condition of the liver, presenting in a suspicious fashion and raising concerns for a primary liver malignancy. RLH should be considered in the differential diagnosis of small hepatic lesions in middle-age females in the absence of any significant risk factors for hepatocellular carcinoma (HCC). RLH tends to be associated with PBC of the liver. Conclusion. RLH of the liver is a rare, hard to diagnose, benign lesion. When intrahepatic, it cannot be easily differentiated from primary liver tumors and frequently requires surgical resection for pathological diagnostic confirmation.http://dx.doi.org/10.1155/2018/9264251
spellingShingle Samantha Seitter
Zachary D. Goodman
Theodore M. Friedman
Timothy R. Shaver
George Younan
Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature
Case Reports in Surgery
title Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature
title_full Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature
title_fullStr Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature
title_full_unstemmed Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature
title_short Intrahepatic Reactive Lymphoid Hyperplasia: A Case Report and Review of the Literature
title_sort intrahepatic reactive lymphoid hyperplasia a case report and review of the literature
url http://dx.doi.org/10.1155/2018/9264251
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