STRUCTURAL AND FUNCTIONAL HEART PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON DIFFERENT BLOOD MIDDLE MASS MOLECULES LEVELS
Aim. To identify the structural and functional heart parameters in patients with chronic heart failure (CHF) depending on severity of endogenous intoxication syndrome that is defined by blood middle mass molecules (MMM) level.Material and methods. In 110 patients with CHF standard clinical, laborato...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Столичная издательская компания
2015-09-01
|
| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/40 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849228011322212352 |
|---|---|
| author | M. A. Kondratyuk O. M. Radchenko |
| author_facet | M. A. Kondratyuk O. M. Radchenko |
| author_sort | M. A. Kondratyuk |
| collection | DOAJ |
| description | Aim. To identify the structural and functional heart parameters in patients with chronic heart failure (CHF) depending on severity of endogenous intoxication syndrome that is defined by blood middle mass molecules (MMM) level.Material and methods. In 110 patients with CHF standard clinical, laboratory and instrumental (echocardiography) examinations were performed. Besides the blood MMM levels were determined in all patients. The patients were divided into three groups with minimal, moderate and severe endogenous intoxication depending on MMM levels.Results. 41.8% of patients had the minimal severity of endogenous intoxication, 39.1% average degree and 19.1% severe intoxication. The patients with the highest MMM levels were specified by low left ventricular ejection fraction (p<0.05), the largest size of right ventricle, the lowest rate of preserved left ventricular function and high rate of diagnosis of increased sizes of the left atrium, interventricular septum and right ventricle.Conclusion. The MMM level can serve as a criterion for prognosis of CHF. Patients with high blood MMM level have the worst prognosis. |
| format | Article |
| id | doaj-art-53e7199309bf432d8d5bee9527f92b59 |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2015-09-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-53e7199309bf432d8d5bee9527f92b592025-08-23T10:00:15ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-0191404310.20996/1819-6446-2013-9-1-40-4340STRUCTURAL AND FUNCTIONAL HEART PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON DIFFERENT BLOOD MIDDLE MASS MOLECULES LEVELSM. A. Kondratyuk0O. M. Radchenko1Lviv National Medical University named after Danylo HalytskyyLviv National Medical University named after Danylo HalytskyyAim. To identify the structural and functional heart parameters in patients with chronic heart failure (CHF) depending on severity of endogenous intoxication syndrome that is defined by blood middle mass molecules (MMM) level.Material and methods. In 110 patients with CHF standard clinical, laboratory and instrumental (echocardiography) examinations were performed. Besides the blood MMM levels were determined in all patients. The patients were divided into three groups with minimal, moderate and severe endogenous intoxication depending on MMM levels.Results. 41.8% of patients had the minimal severity of endogenous intoxication, 39.1% average degree and 19.1% severe intoxication. The patients with the highest MMM levels were specified by low left ventricular ejection fraction (p<0.05), the largest size of right ventricle, the lowest rate of preserved left ventricular function and high rate of diagnosis of increased sizes of the left atrium, interventricular septum and right ventricle.Conclusion. The MMM level can serve as a criterion for prognosis of CHF. Patients with high blood MMM level have the worst prognosis.https://www.rpcardio.online/jour/article/view/40chronic heart failuremiddle mass moleculesendogenous intoxicationstructural and functional parameters of the heart |
| spellingShingle | M. A. Kondratyuk O. M. Radchenko STRUCTURAL AND FUNCTIONAL HEART PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON DIFFERENT BLOOD MIDDLE MASS MOLECULES LEVELS Рациональная фармакотерапия в кардиологии chronic heart failure middle mass molecules endogenous intoxication structural and functional parameters of the heart |
| title | STRUCTURAL AND FUNCTIONAL HEART PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON DIFFERENT BLOOD MIDDLE MASS MOLECULES LEVELS |
| title_full | STRUCTURAL AND FUNCTIONAL HEART PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON DIFFERENT BLOOD MIDDLE MASS MOLECULES LEVELS |
| title_fullStr | STRUCTURAL AND FUNCTIONAL HEART PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON DIFFERENT BLOOD MIDDLE MASS MOLECULES LEVELS |
| title_full_unstemmed | STRUCTURAL AND FUNCTIONAL HEART PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON DIFFERENT BLOOD MIDDLE MASS MOLECULES LEVELS |
| title_short | STRUCTURAL AND FUNCTIONAL HEART PARAMETERS IN PATIENTS WITH CHRONIC HEART FAILURE DEPENDING ON DIFFERENT BLOOD MIDDLE MASS MOLECULES LEVELS |
| title_sort | structural and functional heart parameters in patients with chronic heart failure depending on different blood middle mass molecules levels |
| topic | chronic heart failure middle mass molecules endogenous intoxication structural and functional parameters of the heart |
| url | https://www.rpcardio.online/jour/article/view/40 |
| work_keys_str_mv | AT makondratyuk structuralandfunctionalheartparametersinpatientswithchronicheartfailuredependingondifferentbloodmiddlemassmoleculeslevels AT omradchenko structuralandfunctionalheartparametersinpatientswithchronicheartfailuredependingondifferentbloodmiddlemassmoleculeslevels |