Research adavances of podocyte damage mechanism and traditional Chinese medicine intervention in diabetic kidney disease

Diabetic kidney disease(DKD)is the primary cause of chronic kidney disease and end-stage renal disease and the pathogenesis has remained elusive.Podocyte injury plays a key role in the occurrence and development of DKD.This review summarized the mechanism of podocyte injury in DKD from the aspects o...

Full description

Saved in:
Bibliographic Details
Main Authors: Wen Xiao-chen, Gong Cheng-jun, Ma Xiao-yan
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2021-01-01
Series:Linchuang shenzangbing zazhi
Subjects:
Online Access:http://www.lcszb.com/thesisDetails?columnId=57905023&Fpath=home&index=0
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849313215140331520
author Wen Xiao-chen
Gong Cheng-jun
Ma Xiao-yan
author_facet Wen Xiao-chen
Gong Cheng-jun
Ma Xiao-yan
author_sort Wen Xiao-chen
collection DOAJ
description Diabetic kidney disease(DKD)is the primary cause of chronic kidney disease and end-stage renal disease and the pathogenesis has remained elusive.Podocyte injury plays a key role in the occurrence and development of DKD.This review summarized the mechanism of podocyte injury in DKD from the aspects of metabolic disorders,oxidative stress,inflammatory response and autophagy disorders and the targets and pathways of traditional Chinese medicine intervention.The goal was provides new ideas and references for researches of traditional Chinese medicine in the prevention and treatment of DKD.
format Article
id doaj-art-53e6a90eb8e64e7bb1c67266b6a465aa
institution Kabale University
issn 1671-2390
language zho
publishDate 2021-01-01
publisher Editorial Department of Journal of Clinical Nephrology
record_format Article
series Linchuang shenzangbing zazhi
spelling doaj-art-53e6a90eb8e64e7bb1c67266b6a465aa2025-08-20T03:52:51ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902021-01-0116216757905023Research adavances of podocyte damage mechanism and traditional Chinese medicine intervention in diabetic kidney diseaseWen Xiao-chenGong Cheng-junMa Xiao-yanDiabetic kidney disease(DKD)is the primary cause of chronic kidney disease and end-stage renal disease and the pathogenesis has remained elusive.Podocyte injury plays a key role in the occurrence and development of DKD.This review summarized the mechanism of podocyte injury in DKD from the aspects of metabolic disorders,oxidative stress,inflammatory response and autophagy disorders and the targets and pathways of traditional Chinese medicine intervention.The goal was provides new ideas and references for researches of traditional Chinese medicine in the prevention and treatment of DKD.http://www.lcszb.com/thesisDetails?columnId=57905023&Fpath=home&index=0Diabetic kidney diseasePodocyteTraditional Chinese medicineMetabolic disordersOxidative stressInflammatory responseAutophagy disorders
spellingShingle Wen Xiao-chen
Gong Cheng-jun
Ma Xiao-yan
Research adavances of podocyte damage mechanism and traditional Chinese medicine intervention in diabetic kidney disease
Linchuang shenzangbing zazhi
Diabetic kidney disease
Podocyte
Traditional Chinese medicine
Metabolic disorders
Oxidative stress
Inflammatory response
Autophagy disorders
title Research adavances of podocyte damage mechanism and traditional Chinese medicine intervention in diabetic kidney disease
title_full Research adavances of podocyte damage mechanism and traditional Chinese medicine intervention in diabetic kidney disease
title_fullStr Research adavances of podocyte damage mechanism and traditional Chinese medicine intervention in diabetic kidney disease
title_full_unstemmed Research adavances of podocyte damage mechanism and traditional Chinese medicine intervention in diabetic kidney disease
title_short Research adavances of podocyte damage mechanism and traditional Chinese medicine intervention in diabetic kidney disease
title_sort research adavances of podocyte damage mechanism and traditional chinese medicine intervention in diabetic kidney disease
topic Diabetic kidney disease
Podocyte
Traditional Chinese medicine
Metabolic disorders
Oxidative stress
Inflammatory response
Autophagy disorders
url http://www.lcszb.com/thesisDetails?columnId=57905023&Fpath=home&index=0
work_keys_str_mv AT wenxiaochen researchadavancesofpodocytedamagemechanismandtraditionalchinesemedicineinterventionindiabetickidneydisease
AT gongchengjun researchadavancesofpodocytedamagemechanismandtraditionalchinesemedicineinterventionindiabetickidneydisease
AT maxiaoyan researchadavancesofpodocytedamagemechanismandtraditionalchinesemedicineinterventionindiabetickidneydisease