Regulation of IL-10 production in dendritic cells is controlled by the co-activation of TLR2 and Mincle by Lactiplantibacillus plantarum OLL2712

Regulation of IL-10 production in dendritic cells is controlled by the co-activation of TLR2 and Mincle by Lactiplantibacillus plantarum OLL2712

ABSTRACT We showed that Lactiplantibacillus plantarum OLL2712 (OLL2712) strongly induces interleukin (IL)-10 production in immune cells. Although beneficial effects of this strain have been observed in both mice and humans, the mechanisms underlying IL-10 induction remain unclear. In this study, we...

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Bibliographic Details
Main Authors: Ryuhei Sakabe, Kazumasa Onishi, Junko Mochizuki, Takayuki Toshimitsu, Tomoyuki Shimazu, Shigenobu Kishino, Jun Ogawa, Sho Yamasaki, Toshihiro Sashihara
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:Microbiology Spectrum
Subjects:
lactic acid bacteria
interleukin-10
anti-inflammation
Toll-like receptor 2
macrophage inducible C-type lectin receptor
phagocytosis
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01196-24
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