Momordicine-I suppresses head and neck cancer growth by modulating key metabolic pathways

Momordicine-I suppresses head and neck cancer growth by modulating key metabolic pathways

Abstract One of the hallmarks of cancer is metabolic reprogramming which controls cellular homeostasis and therapy resistance. Here, we investigated the effect of momordicine-I (M-I), a key bioactive compound from Momordica charantia (bitter melon), on metabolic pathways in human head and neck cance...

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Bibliographic Details
Main Authors: Debojyoty Bandyopadhyay, Ellen T. Tran, Ruchi A. Patel, Matthew A. Luetzen, Kevin Cho, Leah P. Shriver, Gary J. Patti, Mark A. Varvares, David A. Ford, Kyle S. McCommis, Ratna B. Ray
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell Communication and Signaling
Subjects:
Momordicine-I
Head and neck cancer
Glycolysis
Lipid metabolism
Metabolites
Autophagy
Online Access:https://doi.org/10.1186/s12964-024-01951-w
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