Chronic gastritis: from histological protocol to substantiation of etiopathogenetic therapy

Gastritis is a reaction of the mucous membrane (MM) of the stomach to damage and is characterized by the formation of inflammatory, dystrophic and dysregenerative changes in the MM of the stomach, as well as atrophy of epithelial cells with replacement of normal glands with fibrous tissue. The progr...

Full description

Saved in:
Bibliographic Details
Main Authors: I. V. Dolgalev, E. N. Kareva, E. A. Lyalyukova, N. V. Pavlova
Format: Article
Language:Russian
Published: Open Systems Publication 2021-06-01
Series:Лечащий Врач
Subjects:
Online Access:https://journal.lvrach.ru/jour/article/view/11
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850065222521323520
author I. V. Dolgalev
E. N. Kareva
E. A. Lyalyukova
N. V. Pavlova
author_facet I. V. Dolgalev
E. N. Kareva
E. A. Lyalyukova
N. V. Pavlova
author_sort I. V. Dolgalev
collection DOAJ
description Gastritis is a reaction of the mucous membrane (MM) of the stomach to damage and is characterized by the formation of inflammatory, dystrophic and dysregenerative changes in the MM of the stomach, as well as atrophy of epithelial cells with replacement of normal glands with fibrous tissue. The progression of chronic gastritis (CG) is accompanied by the development of MM atrophy, dysplasia and becomes a significant factor in the formation of gastric malignant neoplasms. The article presents the modern etiological classification of CG, approaches to the diagnosis of CG, assessing the stage of gastritis on a scale of progressive increase in the likelihood of developing stomach cancer, presents the histological characteristics, and also substantiates etiopathogenetic approaches to the treatment of various forms of CG, including methods for optimizing the eradication therapy of H. pylori infection. which can be used to increase the effectiveness of not only standard triple therapy, but also other anti-Helicobacter treatment regimens. The use of proton pump inhibitors in the treatment of gastritis is considered.
format Article
id doaj-art-53dcbc2c83be45e1af301fa9960875a1
institution DOAJ
issn 1560-5175
2687-1181
language Russian
publishDate 2021-06-01
publisher Open Systems Publication
record_format Article
series Лечащий Врач
spelling doaj-art-53dcbc2c83be45e1af301fa9960875a12025-08-20T02:49:05ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-0102303410.26295/OS.2021.76.84.00610Chronic gastritis: from histological protocol to substantiation of etiopathogenetic therapyI. V. Dolgalev0E. N. Kareva1E. A. Lyalyukova2N. V. Pavlova3FSBEI HE Siberian State Medical University of the Ministry of Health of RussiaN. I. Pirogov Russian National Research Medical University of the Ministry of Helth of Russia; I. M. Sechenov first Moscow state medical universityFFSBEI HE Omsk State Medical University of the Ministry of Health of RussiaFSBEI HE Moscow State University of Medicine and Dentistry n. a. A. I. Evdokimov of the Ministry of Health of RussiaGastritis is a reaction of the mucous membrane (MM) of the stomach to damage and is characterized by the formation of inflammatory, dystrophic and dysregenerative changes in the MM of the stomach, as well as atrophy of epithelial cells with replacement of normal glands with fibrous tissue. The progression of chronic gastritis (CG) is accompanied by the development of MM atrophy, dysplasia and becomes a significant factor in the formation of gastric malignant neoplasms. The article presents the modern etiological classification of CG, approaches to the diagnosis of CG, assessing the stage of gastritis on a scale of progressive increase in the likelihood of developing stomach cancer, presents the histological characteristics, and also substantiates etiopathogenetic approaches to the treatment of various forms of CG, including methods for optimizing the eradication therapy of H. pylori infection. which can be used to increase the effectiveness of not only standard triple therapy, but also other anti-Helicobacter treatment regimens. The use of proton pump inhibitors in the treatment of gastritis is considered.https://journal.lvrach.ru/jour/article/view/11gastritischronic gastritish. pylorihelicobacter pyloriproton pump inhibitors
spellingShingle I. V. Dolgalev
E. N. Kareva
E. A. Lyalyukova
N. V. Pavlova
Chronic gastritis: from histological protocol to substantiation of etiopathogenetic therapy
Лечащий Врач
gastritis
chronic gastritis
h. pylori
helicobacter pylori
proton pump inhibitors
title Chronic gastritis: from histological protocol to substantiation of etiopathogenetic therapy
title_full Chronic gastritis: from histological protocol to substantiation of etiopathogenetic therapy
title_fullStr Chronic gastritis: from histological protocol to substantiation of etiopathogenetic therapy
title_full_unstemmed Chronic gastritis: from histological protocol to substantiation of etiopathogenetic therapy
title_short Chronic gastritis: from histological protocol to substantiation of etiopathogenetic therapy
title_sort chronic gastritis from histological protocol to substantiation of etiopathogenetic therapy
topic gastritis
chronic gastritis
h. pylori
helicobacter pylori
proton pump inhibitors
url https://journal.lvrach.ru/jour/article/view/11
work_keys_str_mv AT ivdolgalev chronicgastritisfromhistologicalprotocoltosubstantiationofetiopathogenetictherapy
AT enkareva chronicgastritisfromhistologicalprotocoltosubstantiationofetiopathogenetictherapy
AT ealyalyukova chronicgastritisfromhistologicalprotocoltosubstantiationofetiopathogenetictherapy
AT nvpavlova chronicgastritisfromhistologicalprotocoltosubstantiationofetiopathogenetictherapy