Pain Management in People with Diabetes-Related Chronic Limb-Threatening Ischemia
Management of neuropathic pain in people with diabetes has been widely investigated. However, little attention was paid to address ischemic-related pain in patients with diabetes mellitus who suffered from chronic limb-threatening ischemia (CLTI), the end stage of lower extremity arterial disease (L...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2021/6699292 |
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| _version_ | 1849406382200061952 |
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| author | Xiaoyan Jiang Yi Yuan Yu Ma Miao Zhong Chenzhen Du Johnson Boey David G. Armstrong Wuquan Deng Xiaodong Duan |
| author_facet | Xiaoyan Jiang Yi Yuan Yu Ma Miao Zhong Chenzhen Du Johnson Boey David G. Armstrong Wuquan Deng Xiaodong Duan |
| author_sort | Xiaoyan Jiang |
| collection | DOAJ |
| description | Management of neuropathic pain in people with diabetes has been widely investigated. However, little attention was paid to address ischemic-related pain in patients with diabetes mellitus who suffered from chronic limb-threatening ischemia (CLTI), the end stage of lower extremity arterial disease (LEAD). Pain management has a tremendous influence on patients’ quality of life and prognosis. Poor management of this type of pain owing to the lack of full understanding undermines patients’ physical and mental quality of life, which often results in a grim prognosis, such as depression, myocardial infarction, lower limb amputation, and even mortality. In the present article, we review the current strategy in the pain management of diabetes-related CLTI. The endovascular therapy, pharmacological therapies, and other optional methods could be selected following comprehensive assessments to mitigate ischemic-related pain, in line with our current clinical practice. It is very important for clinicians and patients to strengthen the understanding and build intervention strategy in ischemic pain management and possible adverse consequence. |
| format | Article |
| id | doaj-art-53dc69beeb0e4ae69c3b1b53ef8988a8 |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-53dc69beeb0e4ae69c3b1b53ef8988a82025-08-20T03:36:23ZengWileyJournal of Diabetes Research2314-67452314-67532021-01-01202110.1155/2021/66992926699292Pain Management in People with Diabetes-Related Chronic Limb-Threatening IschemiaXiaoyan Jiang0Yi Yuan1Yu Ma2Miao Zhong3Chenzhen Du4Johnson Boey5David G. Armstrong6Wuquan Deng7Xiaodong Duan8Department of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, ChinaDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, ChinaDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, ChinaDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, ChinaDepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, ChinaDepartment of Podiatry, National University of Hospital Singapore, 169608, SingaporeKeck School of Medicine of University of Southern California, Los Angeles, CA 90033, USADepartment of Endocrinology, Diabetic Foot Center, Chongqing University Central Hospital, Chongqing Emergency Medical Center, Chongqing 400014, ChinaDepartment of Rehabilitation, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, ChinaManagement of neuropathic pain in people with diabetes has been widely investigated. However, little attention was paid to address ischemic-related pain in patients with diabetes mellitus who suffered from chronic limb-threatening ischemia (CLTI), the end stage of lower extremity arterial disease (LEAD). Pain management has a tremendous influence on patients’ quality of life and prognosis. Poor management of this type of pain owing to the lack of full understanding undermines patients’ physical and mental quality of life, which often results in a grim prognosis, such as depression, myocardial infarction, lower limb amputation, and even mortality. In the present article, we review the current strategy in the pain management of diabetes-related CLTI. The endovascular therapy, pharmacological therapies, and other optional methods could be selected following comprehensive assessments to mitigate ischemic-related pain, in line with our current clinical practice. It is very important for clinicians and patients to strengthen the understanding and build intervention strategy in ischemic pain management and possible adverse consequence.http://dx.doi.org/10.1155/2021/6699292 |
| spellingShingle | Xiaoyan Jiang Yi Yuan Yu Ma Miao Zhong Chenzhen Du Johnson Boey David G. Armstrong Wuquan Deng Xiaodong Duan Pain Management in People with Diabetes-Related Chronic Limb-Threatening Ischemia Journal of Diabetes Research |
| title | Pain Management in People with Diabetes-Related Chronic Limb-Threatening Ischemia |
| title_full | Pain Management in People with Diabetes-Related Chronic Limb-Threatening Ischemia |
| title_fullStr | Pain Management in People with Diabetes-Related Chronic Limb-Threatening Ischemia |
| title_full_unstemmed | Pain Management in People with Diabetes-Related Chronic Limb-Threatening Ischemia |
| title_short | Pain Management in People with Diabetes-Related Chronic Limb-Threatening Ischemia |
| title_sort | pain management in people with diabetes related chronic limb threatening ischemia |
| url | http://dx.doi.org/10.1155/2021/6699292 |
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