Successful Treatment of Incomplete Susac Syndrome with Simultaneous Corticosteroids and Plasmapheresis Followed by Rituximab

We present a case report of a patient with incomplete Susac syndrome. He had cognitive impairment, corpus callosum lesions, and vestibulocochlear dysfunction on brainstem auditory evoked responses. He was treated with methylprednisolone and plasmapheresis, improved, and then, also received rituximab...

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Main Authors: Mick B. Reedy, Yanping Wang, Brad R. Beinlich, William Nicholas Rose
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2021/5591559
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author Mick B. Reedy
Yanping Wang
Brad R. Beinlich
William Nicholas Rose
author_facet Mick B. Reedy
Yanping Wang
Brad R. Beinlich
William Nicholas Rose
author_sort Mick B. Reedy
collection DOAJ
description We present a case report of a patient with incomplete Susac syndrome. He had cognitive impairment, corpus callosum lesions, and vestibulocochlear dysfunction on brainstem auditory evoked responses. He was treated with methylprednisolone and plasmapheresis, improved, and then, also received rituximab. His improvement has been lasting as of this writing. This case shares our experience with a successful treatment of this rare condition that is incompletely understood and lacks well-established treatment guidelines.
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institution Kabale University
issn 2090-6668
2090-6676
language English
publishDate 2021-01-01
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spelling doaj-art-53db6fb834cc4864a513bfd0f879460d2025-02-03T05:44:44ZengWileyCase Reports in Neurological Medicine2090-66682090-66762021-01-01202110.1155/2021/55915595591559Successful Treatment of Incomplete Susac Syndrome with Simultaneous Corticosteroids and Plasmapheresis Followed by RituximabMick B. Reedy0Yanping Wang1Brad R. Beinlich2William Nicholas Rose3Department of Neurology, University of Wisconsin Hospital, 600 Highland Ave, Madison, WI 53792, USADepartment of Pathology, University of Wisconsin Hospital, 600 Highland Ave, Madison, WI 53792, USADepartment of Neurology, University of Wisconsin Hospital, 600 Highland Ave, Madison, WI 53792, USADepartment of Pathology, University of Wisconsin Hospital, 600 Highland Ave, Madison, WI 53792, USAWe present a case report of a patient with incomplete Susac syndrome. He had cognitive impairment, corpus callosum lesions, and vestibulocochlear dysfunction on brainstem auditory evoked responses. He was treated with methylprednisolone and plasmapheresis, improved, and then, also received rituximab. His improvement has been lasting as of this writing. This case shares our experience with a successful treatment of this rare condition that is incompletely understood and lacks well-established treatment guidelines.http://dx.doi.org/10.1155/2021/5591559
spellingShingle Mick B. Reedy
Yanping Wang
Brad R. Beinlich
William Nicholas Rose
Successful Treatment of Incomplete Susac Syndrome with Simultaneous Corticosteroids and Plasmapheresis Followed by Rituximab
Case Reports in Neurological Medicine
title Successful Treatment of Incomplete Susac Syndrome with Simultaneous Corticosteroids and Plasmapheresis Followed by Rituximab
title_full Successful Treatment of Incomplete Susac Syndrome with Simultaneous Corticosteroids and Plasmapheresis Followed by Rituximab
title_fullStr Successful Treatment of Incomplete Susac Syndrome with Simultaneous Corticosteroids and Plasmapheresis Followed by Rituximab
title_full_unstemmed Successful Treatment of Incomplete Susac Syndrome with Simultaneous Corticosteroids and Plasmapheresis Followed by Rituximab
title_short Successful Treatment of Incomplete Susac Syndrome with Simultaneous Corticosteroids and Plasmapheresis Followed by Rituximab
title_sort successful treatment of incomplete susac syndrome with simultaneous corticosteroids and plasmapheresis followed by rituximab
url http://dx.doi.org/10.1155/2021/5591559
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