Evaluation of Multiple Sclerosis from the Perspective of Conventional Medicine and Traditional Persian Medicine, Considering the Concept of Hemorheology

Multiple sclerosis (MS) is a persistent inflammatory disorder of uncertain etiology. Certain observations suggest that the pathology might not solely stem from primary immune dysregulation. Advanced imaging techniques reveal decreased cerebral blood flow in MS subjects compared to healthy controls,...

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Main Authors: Mahdi Yaseliani, Hossein Rezaeizadeh, Abdolreaza Naser Moghadasi, Mohammad Ali Sahraian, Mehrdad Karimi, Mahdi Alizadeh Vaghasloo
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2025-06-01
Series:Traditional and Integrative Medicine
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Online Access:https://jtim.tums.ac.ir/index.php/jtim/article/view/1597
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author Mahdi Yaseliani
Hossein Rezaeizadeh
Abdolreaza Naser Moghadasi
Mohammad Ali Sahraian
Mehrdad Karimi
Mahdi Alizadeh Vaghasloo
author_facet Mahdi Yaseliani
Hossein Rezaeizadeh
Abdolreaza Naser Moghadasi
Mohammad Ali Sahraian
Mehrdad Karimi
Mahdi Alizadeh Vaghasloo
author_sort Mahdi Yaseliani
collection DOAJ
description Multiple sclerosis (MS) is a persistent inflammatory disorder of uncertain etiology. Certain observations suggest that the pathology might not solely stem from primary immune dysregulation. Advanced imaging techniques reveal decreased cerebral blood flow in MS subjects compared to healthy controls, suggesting a widespread cerebral hypoperfusion present from early to advanced disease stages. One of the effective factors in reducing tissue perfusion is a change in the rheological properties of blood, which has been mentioned in recent articles. By attention to this concept in complementary and traditional medicine, including Persian medicine, this can be a common point that connects the view of Traditional Persian Medicine (TPM) on MS to the existing hypotheses about the role of hemorheology in the development of MS. For this study, a two-step literature search was conducted. The initial search focused on concepts related to MS disease and changes in blood consistency in most important TPM texts. For the second inquiry, the PubMed, ScienceDirect, Scopus, and Google Scholar databases were explored using the keywords related to MS and blood viscosity concepts. TPM, believes that the imbalance of the four Humors in the body, changes the physical properties of blood, leading to changes in the tissues blood supply and can cause nerve injury in the long run. On the other hand, in modern physiology, some evidence shows that circulatory disorders precede immune responses in the development of MS and the reaction of the immune system is actually secondary to the ischemia created as a result of reduced blood supply. We believe that discussing Hemorheology, not only in MS, but also in many other diseases, can open new horizons for knowing the root cause of the disease and thus discovering better treatments.
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spelling doaj-art-53d9fd519b9a416fac343df40f0bebd42025-08-20T02:36:31ZengTehran University of Medical SciencesTraditional and Integrative Medicine2476-51042476-51122025-06-0110210.18502/tim.v10i2.19062Evaluation of Multiple Sclerosis from the Perspective of Conventional Medicine and Traditional Persian Medicine, Considering the Concept of HemorheologyMahdi Yaseliani0Hossein Rezaeizadeh1Abdolreaza Naser Moghadasi2Mohammad Ali Sahraian3Mehrdad Karimi4Mahdi Alizadeh Vaghasloo5Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, IranMultiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, IranMultiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, IranDepartment of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, IranDepartment of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran AND Persian Medicine Network (PMN), Universal Scientific Education and Research Network (USERN), Tehran, Iran Multiple sclerosis (MS) is a persistent inflammatory disorder of uncertain etiology. Certain observations suggest that the pathology might not solely stem from primary immune dysregulation. Advanced imaging techniques reveal decreased cerebral blood flow in MS subjects compared to healthy controls, suggesting a widespread cerebral hypoperfusion present from early to advanced disease stages. One of the effective factors in reducing tissue perfusion is a change in the rheological properties of blood, which has been mentioned in recent articles. By attention to this concept in complementary and traditional medicine, including Persian medicine, this can be a common point that connects the view of Traditional Persian Medicine (TPM) on MS to the existing hypotheses about the role of hemorheology in the development of MS. For this study, a two-step literature search was conducted. The initial search focused on concepts related to MS disease and changes in blood consistency in most important TPM texts. For the second inquiry, the PubMed, ScienceDirect, Scopus, and Google Scholar databases were explored using the keywords related to MS and blood viscosity concepts. TPM, believes that the imbalance of the four Humors in the body, changes the physical properties of blood, leading to changes in the tissues blood supply and can cause nerve injury in the long run. On the other hand, in modern physiology, some evidence shows that circulatory disorders precede immune responses in the development of MS and the reaction of the immune system is actually secondary to the ischemia created as a result of reduced blood supply. We believe that discussing Hemorheology, not only in MS, but also in many other diseases, can open new horizons for knowing the root cause of the disease and thus discovering better treatments. https://jtim.tums.ac.ir/index.php/jtim/article/view/1597Multiple SclerosisTraditional Persian MedicineHemorheology
spellingShingle Mahdi Yaseliani
Hossein Rezaeizadeh
Abdolreaza Naser Moghadasi
Mohammad Ali Sahraian
Mehrdad Karimi
Mahdi Alizadeh Vaghasloo
Evaluation of Multiple Sclerosis from the Perspective of Conventional Medicine and Traditional Persian Medicine, Considering the Concept of Hemorheology
Traditional and Integrative Medicine
Multiple Sclerosis
Traditional Persian Medicine
Hemorheology
title Evaluation of Multiple Sclerosis from the Perspective of Conventional Medicine and Traditional Persian Medicine, Considering the Concept of Hemorheology
title_full Evaluation of Multiple Sclerosis from the Perspective of Conventional Medicine and Traditional Persian Medicine, Considering the Concept of Hemorheology
title_fullStr Evaluation of Multiple Sclerosis from the Perspective of Conventional Medicine and Traditional Persian Medicine, Considering the Concept of Hemorheology
title_full_unstemmed Evaluation of Multiple Sclerosis from the Perspective of Conventional Medicine and Traditional Persian Medicine, Considering the Concept of Hemorheology
title_short Evaluation of Multiple Sclerosis from the Perspective of Conventional Medicine and Traditional Persian Medicine, Considering the Concept of Hemorheology
title_sort evaluation of multiple sclerosis from the perspective of conventional medicine and traditional persian medicine considering the concept of hemorheology
topic Multiple Sclerosis
Traditional Persian Medicine
Hemorheology
url https://jtim.tums.ac.ir/index.php/jtim/article/view/1597
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