Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndrome
After recovering from severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2) acute infection, some patients with corona virus disease 2019 (COVID-19) still are affected by post-acute COVID-19 syndrome (PACS). Traditional Chinese medicine (TCM) has played an important role in the recovery pe...
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| Format: | Article |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1588037/full |
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| author | Zhan Li Zhan Li Yingqi Liu Wei Ding Yue Liu Wang Li Shanshan Guan Xianjun Liu Guizhen Wang Qiong Liu Chunwa Jiang Xinli Peng Hao Li Zhandong Li Jing Li |
| author_facet | Zhan Li Zhan Li Yingqi Liu Wei Ding Yue Liu Wang Li Shanshan Guan Xianjun Liu Guizhen Wang Qiong Liu Chunwa Jiang Xinli Peng Hao Li Zhandong Li Jing Li |
| author_sort | Zhan Li |
| collection | DOAJ |
| description | After recovering from severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2) acute infection, some patients with corona virus disease 2019 (COVID-19) still are affected by post-acute COVID-19 syndrome (PACS). Traditional Chinese medicine (TCM) has played an important role in the recovery period of COVID-19. As a unique type of Chinese botanical drugs, foods with property of food and medicine homology (FMH) has the dual characteristics of drug and food, which has advantages over usual drugs in safety and daily application. This review analyzed a total of 290 peer-reviewed publications on the progress of dozens of formulas and single botanical drugs, which were systematically collected from the electronic scientific databases, including PubMed, Web of Science, and China National Knowledge Infrastructure (CNKI), as well as other literature sources, such as classic Chinese medicine books. The symptoms of PACS and the advancements in the application of FMH foods in PACS intervention are summarized, and the challenges in the regulatory characteristics and food safety are further discussed. It is expected that the application of FMH foods would bring new opportunity for the treatment and daily intervention of PACS, and this review provides a foundation for the development of PACS intervention foods. |
| format | Article |
| id | doaj-art-53d03607fcf54e6bb45451c6f0d8b64a |
| institution | Kabale University |
| issn | 1663-9812 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj-art-53d03607fcf54e6bb45451c6f0d8b64a2025-08-20T03:28:59ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-07-011610.3389/fphar.2025.15880371588037Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndromeZhan Li0Zhan Li1Yingqi Liu2Wei Ding3Yue Liu4Wang Li5Shanshan Guan6Xianjun Liu7Guizhen Wang8Qiong Liu9Chunwa Jiang10Xinli Peng11Hao Li12Zhandong Li13Jing Li14School of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Chemistry and Life Sciences, Changchun University of Technology, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaEngineering Research Center of Edible and Medicinal Fungi, Ministry of Education, Jilin Agricultural University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Biological and Food Engineering, Jilin Engineering Normal University, Changchun, ChinaSchool of Computer Science, Baicheng Normal University, Baicheng, ChinaAfter recovering from severe acute respiratory syndrome of coronavirus 2 (SARS-CoV-2) acute infection, some patients with corona virus disease 2019 (COVID-19) still are affected by post-acute COVID-19 syndrome (PACS). Traditional Chinese medicine (TCM) has played an important role in the recovery period of COVID-19. As a unique type of Chinese botanical drugs, foods with property of food and medicine homology (FMH) has the dual characteristics of drug and food, which has advantages over usual drugs in safety and daily application. This review analyzed a total of 290 peer-reviewed publications on the progress of dozens of formulas and single botanical drugs, which were systematically collected from the electronic scientific databases, including PubMed, Web of Science, and China National Knowledge Infrastructure (CNKI), as well as other literature sources, such as classic Chinese medicine books. The symptoms of PACS and the advancements in the application of FMH foods in PACS intervention are summarized, and the challenges in the regulatory characteristics and food safety are further discussed. It is expected that the application of FMH foods would bring new opportunity for the treatment and daily intervention of PACS, and this review provides a foundation for the development of PACS intervention foods.https://www.frontiersin.org/articles/10.3389/fphar.2025.1588037/fullfood and medicine homologypost-acute COVID-19 syndromefood interventionfood safetyfood development |
| spellingShingle | Zhan Li Zhan Li Yingqi Liu Wei Ding Yue Liu Wang Li Shanshan Guan Xianjun Liu Guizhen Wang Qiong Liu Chunwa Jiang Xinli Peng Hao Li Zhandong Li Jing Li Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndrome Frontiers in Pharmacology food and medicine homology post-acute COVID-19 syndrome food intervention food safety food development |
| title | Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndrome |
| title_full | Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndrome |
| title_fullStr | Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndrome |
| title_full_unstemmed | Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndrome |
| title_short | Food and medicine homology: a potential nutritional intervention strategy for post-acute COVID-19 syndrome |
| title_sort | food and medicine homology a potential nutritional intervention strategy for post acute covid 19 syndrome |
| topic | food and medicine homology post-acute COVID-19 syndrome food intervention food safety food development |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2025.1588037/full |
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