Prognostic analysis and mechanistic exploration of the autophagy-related exosome genes ITGA3, ITGB4, and PTK6 in pancreatic ductal adenocarcinoma

Prognostic analysis and mechanistic exploration of the autophagy-related exosome genes ITGA3, ITGB4, and PTK6 in pancreatic ductal adenocarcinoma

Abstract Pancreatic cancer (PC) is a highly malignant tumor with an extremely poor prognosis, but early diagnosis and treatment can significantly improve prognosis. This study aimed to screen autophagy-related exosome genes associated with poor prognosis in PC and to explore the underlying mechanism...

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Bibliographic Details
Main Authors: Lunbing Liang, Pengcheng Guo, Mingming Xiao, Fuqiang Zu, Guoliang Hao, Chaochun Zhang, Qingfeng Liu
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
Pancreatic cancer
Exosomes
Autophagy
Integrins α3
Integrin β4
Protein tyrosine kinase 6
Online Access:https://doi.org/10.1007/s12672-025-03061-6
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