Parathyroid function and cardiovascular remodeling in arterial hypertension patients
Aim. To investigate structure and function of left ventriculum (LV) and brachial artery (BA) in arterial hypertension (AH) patients, according to blood levels of parathyroid hormone (PTH).Material and methods. In total, 95 untreated patients with Stage I-III AH were examined. Blood PTH, total calciu...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2008-04-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1298 |
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| author | B. G. Iskenderov L. F. Burmistrova T. V. Lokhina G. N. Abramova N. A. Timofeeva T. M. Shibaeva |
| author_facet | B. G. Iskenderov L. F. Burmistrova T. V. Lokhina G. N. Abramova N. A. Timofeeva T. M. Shibaeva |
| author_sort | B. G. Iskenderov |
| collection | DOAJ |
| description | Aim. To investigate structure and function of left ventriculum (LV) and brachial artery (BA) in arterial hypertension (AH) patients, according to blood levels of parathyroid hormone (PTH).Material and methods. In total, 95 untreated patients with Stage I-III AH were examined. Blood PTH, total calcium levels, and 24-hour urine calcium excretion were measured. All participants underwent Doppler echocardiography, 24-hour blood pressure monitoring (BPM), and BA ultrasound. According to PTH levels, the patients were divided into three groups: Group I – 0-25 pg/ml, Group II – 26-50 pg/ml, and Group III – 51 pg/ml.Results. LV hypertrophy prevalence in Group III was 80,6%, in Group I – 43,7%. In “dippers” (24-hour BPM data), PTH level and 24-hour urine calcium excretion were 1,5 times lower than in “non-dippers”. Comparing to Group I, Group III demonstrated significantly greater intima-media thickness (+17,8%) and linear blood flowvelocity (+19,7%), but lower BA diameter (417,3%) and endothelium-dependent vasodilatation (415,5%).Conclusion. PTH levels correlated with prevalence and severity of LV and BA remodeling. |
| format | Article |
| id | doaj-art-53b80c85cbe5425bbd8a6adbce9dc893 |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2008-04-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-53b80c85cbe5425bbd8a6adbce9dc8932025-08-20T03:57:09Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252008-04-017223271008Parathyroid function and cardiovascular remodeling in arterial hypertension patientsB. G. Iskenderov0L. F. Burmistrova1T. V. Lokhina2G. N. Abramova3N. A. Timofeeva4T. M. Shibaeva5Penza Institute of Continuous Medical Education. PenzaPenza Institute of Continuous Medical Education. PenzaPenza Institute of Continuous Medical Education. PenzaPenza Institute of Continuous Medical Education. PenzaPenza Institute of Continuous Medical Education. PenzaPenza Institute of Continuous Medical Education. PenzaAim. To investigate structure and function of left ventriculum (LV) and brachial artery (BA) in arterial hypertension (AH) patients, according to blood levels of parathyroid hormone (PTH).Material and methods. In total, 95 untreated patients with Stage I-III AH were examined. Blood PTH, total calcium levels, and 24-hour urine calcium excretion were measured. All participants underwent Doppler echocardiography, 24-hour blood pressure monitoring (BPM), and BA ultrasound. According to PTH levels, the patients were divided into three groups: Group I – 0-25 pg/ml, Group II – 26-50 pg/ml, and Group III – 51 pg/ml.Results. LV hypertrophy prevalence in Group III was 80,6%, in Group I – 43,7%. In “dippers” (24-hour BPM data), PTH level and 24-hour urine calcium excretion were 1,5 times lower than in “non-dippers”. Comparing to Group I, Group III demonstrated significantly greater intima-media thickness (+17,8%) and linear blood flowvelocity (+19,7%), but lower BA diameter (417,3%) and endothelium-dependent vasodilatation (415,5%).Conclusion. PTH levels correlated with prevalence and severity of LV and BA remodeling.https://cardiovascular.elpub.ru/jour/article/view/1298arterial hypertensionparathyroid hormonecardiovascular remodelingparathyroid gland |
| spellingShingle | B. G. Iskenderov L. F. Burmistrova T. V. Lokhina G. N. Abramova N. A. Timofeeva T. M. Shibaeva Parathyroid function and cardiovascular remodeling in arterial hypertension patients Кардиоваскулярная терапия и профилактика arterial hypertension parathyroid hormone cardiovascular remodeling parathyroid gland |
| title | Parathyroid function and cardiovascular remodeling in arterial hypertension patients |
| title_full | Parathyroid function and cardiovascular remodeling in arterial hypertension patients |
| title_fullStr | Parathyroid function and cardiovascular remodeling in arterial hypertension patients |
| title_full_unstemmed | Parathyroid function and cardiovascular remodeling in arterial hypertension patients |
| title_short | Parathyroid function and cardiovascular remodeling in arterial hypertension patients |
| title_sort | parathyroid function and cardiovascular remodeling in arterial hypertension patients |
| topic | arterial hypertension parathyroid hormone cardiovascular remodeling parathyroid gland |
| url | https://cardiovascular.elpub.ru/jour/article/view/1298 |
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