Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview
Cisplatin cis-(diammine)dichloridoplatinum(II) (CDDP) is the first platinum-based complex approved by the food and drug administration (FDA) of the United States (US). Cisplatin is the first line chemotherapeutic agent used alone or combined with radiations or other anti-cancer agents for a broad ra...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-12-01
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| Series: | Artificial Cells, Nanomedicine, and Biotechnology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/21691401.2019.1604535 |
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| author | Muhammad Asim Farooq Md Aquib Anum Farooq Daulat Haleem Khan Mily Bazezy Joelle Maviah Mensura Sied Filli Samuel Kesse Kofi Oti Boakye-Yiadom Rukhshona Mavlyanova Amna Parveen Bo Wang |
| author_facet | Muhammad Asim Farooq Md Aquib Anum Farooq Daulat Haleem Khan Mily Bazezy Joelle Maviah Mensura Sied Filli Samuel Kesse Kofi Oti Boakye-Yiadom Rukhshona Mavlyanova Amna Parveen Bo Wang |
| author_sort | Muhammad Asim Farooq |
| collection | DOAJ |
| description | Cisplatin cis-(diammine)dichloridoplatinum(II) (CDDP) is the first platinum-based complex approved by the food and drug administration (FDA) of the United States (US). Cisplatin is the first line chemotherapeutic agent used alone or combined with radiations or other anti-cancer agents for a broad range of cancers such as lung, head and neck. Aroplatin™, Lipoplatin™ and SPI-077 are PEGylated liposome-based nano-formulations that are still under clinical trials. They have many limitations, for example, poor aqueous solubility, drug resistance and toxicities, which can be overcome by encapsulating the cisplatin in Nemours nanocarriers. The extensive literature from different electronic databases covers the different nano-delivery systems that are developed for cisplatin. This review critically emphasizes on the recent advancement, development, innovations and updated literature reported for different carrier systems for CDDP. |
| format | Article |
| id | doaj-art-53b3cffdb5e741e9ad336e910330781f |
| institution | Kabale University |
| issn | 2169-1401 2169-141X |
| language | English |
| publishDate | 2019-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Artificial Cells, Nanomedicine, and Biotechnology |
| spelling | doaj-art-53b3cffdb5e741e9ad336e910330781f2025-08-20T03:51:24ZengTaylor & Francis GroupArtificial Cells, Nanomedicine, and Biotechnology2169-14012169-141X2019-12-014711674169210.1080/21691401.2019.1604535Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overviewMuhammad Asim Farooq0Md Aquib1Anum Farooq2Daulat Haleem Khan3Mily Bazezy Joelle Maviah4Mensura Sied Filli5Samuel Kesse6Kofi Oti Boakye-Yiadom7Rukhshona Mavlyanova8Amna Parveen9Bo Wang10Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaDepartment of Chemistry, Government College University, Faisalabad, PakistanDepartment of Pharmacy, Lahore College of Pharmaceutical Sciences, Lahore, Pakistan;Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaCollege of Pharmacy, Gachon University, Hambakmoero, Yeonsu-gu, Incheon, KoreaDepartment of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing, PR ChinaCisplatin cis-(diammine)dichloridoplatinum(II) (CDDP) is the first platinum-based complex approved by the food and drug administration (FDA) of the United States (US). Cisplatin is the first line chemotherapeutic agent used alone or combined with radiations or other anti-cancer agents for a broad range of cancers such as lung, head and neck. Aroplatin™, Lipoplatin™ and SPI-077 are PEGylated liposome-based nano-formulations that are still under clinical trials. They have many limitations, for example, poor aqueous solubility, drug resistance and toxicities, which can be overcome by encapsulating the cisplatin in Nemours nanocarriers. The extensive literature from different electronic databases covers the different nano-delivery systems that are developed for cisplatin. This review critically emphasizes on the recent advancement, development, innovations and updated literature reported for different carrier systems for CDDP.https://www.tandfonline.com/doi/10.1080/21691401.2019.1604535Cisplatindrug delivery systempolymeric nanoparticlescancernanotechnologyinorganic carriers |
| spellingShingle | Muhammad Asim Farooq Md Aquib Anum Farooq Daulat Haleem Khan Mily Bazezy Joelle Maviah Mensura Sied Filli Samuel Kesse Kofi Oti Boakye-Yiadom Rukhshona Mavlyanova Amna Parveen Bo Wang Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview Artificial Cells, Nanomedicine, and Biotechnology Cisplatin drug delivery system polymeric nanoparticles cancer nanotechnology inorganic carriers |
| title | Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview |
| title_full | Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview |
| title_fullStr | Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview |
| title_full_unstemmed | Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview |
| title_short | Recent progress in nanotechnology-based novel drug delivery systems in designing of cisplatin for cancer therapy: an overview |
| title_sort | recent progress in nanotechnology based novel drug delivery systems in designing of cisplatin for cancer therapy an overview |
| topic | Cisplatin drug delivery system polymeric nanoparticles cancer nanotechnology inorganic carriers |
| url | https://www.tandfonline.com/doi/10.1080/21691401.2019.1604535 |
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