Peripheral Neuropathy: A Rare Side Effect of Metronidazole
Metronidazole (MTZ) is a potent drug used against protozoa such as Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and Balantidium coli, anaerobic bacteria, amebic liver abscess, bacterial meningitis, infection of the bone, and infectious disorder of the joint. Common side effects of...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer – Medknow Publications
2020-07-01
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| Series: | Journal of Integrated Health Sciences |
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| Online Access: | https://journals.lww.com/10.4103/JIHS.JIHS_19_19 |
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| author | Nisarg Rajeshkumar Hajariwala Vikas R. Chandrakar Jitendra D. Lakhani |
| author_facet | Nisarg Rajeshkumar Hajariwala Vikas R. Chandrakar Jitendra D. Lakhani |
| author_sort | Nisarg Rajeshkumar Hajariwala |
| collection | DOAJ |
| description | Metronidazole (MTZ) is a potent drug used against protozoa such as Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and Balantidium coli, anaerobic bacteria, amebic liver abscess, bacterial meningitis, infection of the bone, and infectious disorder of the joint. Common side effects of MTZ include mild abdominal pain, headache, nausea, and persistent metallic taste, while other serious and rare side effects include pseudomembranous colitis, seizures, encephalopathy, and peripheral neuropathy. A case of MTZ-induced peripheral neuropathy has been included in this article. A patient was prescribed MTZ for liver abscess for 4 weeks; the patient developed peripheral neuropathy in 15 days; immediately, he reached the hospital and MTZ was withdrawn. He has then been prescribed pregabalin to treat peripheral neuropathy. The patient improved in 4 days on this treatment and was discharged from the hospital. This study concludes that MTZ has a rare side effect of peripheral neuropathy. |
| format | Article |
| id | doaj-art-53b002bd91104ca58942680edd390616 |
| institution | OA Journals |
| issn | 2347-6486 2347-6494 |
| language | English |
| publishDate | 2020-07-01 |
| publisher | Wolters Kluwer – Medknow Publications |
| record_format | Article |
| series | Journal of Integrated Health Sciences |
| spelling | doaj-art-53b002bd91104ca58942680edd3906162025-08-20T02:16:05ZengWolters Kluwer – Medknow PublicationsJournal of Integrated Health Sciences2347-64862347-64942020-07-0182838510.4103/JIHS.JIHS_19_19Peripheral Neuropathy: A Rare Side Effect of MetronidazoleNisarg Rajeshkumar HajariwalaVikas R. ChandrakarJitendra D. LakhaniMetronidazole (MTZ) is a potent drug used against protozoa such as Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis, and Balantidium coli, anaerobic bacteria, amebic liver abscess, bacterial meningitis, infection of the bone, and infectious disorder of the joint. Common side effects of MTZ include mild abdominal pain, headache, nausea, and persistent metallic taste, while other serious and rare side effects include pseudomembranous colitis, seizures, encephalopathy, and peripheral neuropathy. A case of MTZ-induced peripheral neuropathy has been included in this article. A patient was prescribed MTZ for liver abscess for 4 weeks; the patient developed peripheral neuropathy in 15 days; immediately, he reached the hospital and MTZ was withdrawn. He has then been prescribed pregabalin to treat peripheral neuropathy. The patient improved in 4 days on this treatment and was discharged from the hospital. This study concludes that MTZ has a rare side effect of peripheral neuropathy.https://journals.lww.com/10.4103/JIHS.JIHS_19_19drug-induced peripheral neuropathymetronidazoleperipheral neuropathy |
| spellingShingle | Nisarg Rajeshkumar Hajariwala Vikas R. Chandrakar Jitendra D. Lakhani Peripheral Neuropathy: A Rare Side Effect of Metronidazole Journal of Integrated Health Sciences drug-induced peripheral neuropathy metronidazole peripheral neuropathy |
| title | Peripheral Neuropathy: A Rare Side Effect of Metronidazole |
| title_full | Peripheral Neuropathy: A Rare Side Effect of Metronidazole |
| title_fullStr | Peripheral Neuropathy: A Rare Side Effect of Metronidazole |
| title_full_unstemmed | Peripheral Neuropathy: A Rare Side Effect of Metronidazole |
| title_short | Peripheral Neuropathy: A Rare Side Effect of Metronidazole |
| title_sort | peripheral neuropathy a rare side effect of metronidazole |
| topic | drug-induced peripheral neuropathy metronidazole peripheral neuropathy |
| url | https://journals.lww.com/10.4103/JIHS.JIHS_19_19 |
| work_keys_str_mv | AT nisargrajeshkumarhajariwala peripheralneuropathyararesideeffectofmetronidazole AT vikasrchandrakar peripheralneuropathyararesideeffectofmetronidazole AT jitendradlakhani peripheralneuropathyararesideeffectofmetronidazole |