Primary Follicular Lymphoma of the Duodenum with Erosions as Atypical Macroscopic Features

A 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions with peripheral whitish edematous mucosa. Initial biopsy specimens taken from the erosions revealed insufficient numbers of lymphoma cells...

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Main Authors: Keiko Takeuchi, Masaya Iwamuro, Atsushi Imagawa, Yoshitsugu Kubota, Katsuya Miyatani, Katsuyoshi Takata, Hiroyuki Okada
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/582607
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author Keiko Takeuchi
Masaya Iwamuro
Atsushi Imagawa
Yoshitsugu Kubota
Katsuya Miyatani
Katsuyoshi Takata
Hiroyuki Okada
author_facet Keiko Takeuchi
Masaya Iwamuro
Atsushi Imagawa
Yoshitsugu Kubota
Katsuya Miyatani
Katsuyoshi Takata
Hiroyuki Okada
author_sort Keiko Takeuchi
collection DOAJ
description A 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions with peripheral whitish edematous mucosa. Initial biopsy specimens taken from the erosions revealed insufficient numbers of lymphoma cells for histological diagnosis. Subsequent biopsy specimens from the peripheral mucosa containing the whitish enlarged villi showed infiltration of the lymphoma cells forming lymphoid follicles, which led us to the appropriate diagnosis. This case indicates that endoscopists should take biopsy samples from the peripheral mucosa with whitish enlarged villi rather than erosions in the rare instances that erosions appear as the main macroscopic feature of intestinal follicular lymphoma.
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spelling doaj-art-53ae4899cd914d9e8b7a19696102d0fb2025-08-20T02:05:31ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/582607582607Primary Follicular Lymphoma of the Duodenum with Erosions as Atypical Macroscopic FeaturesKeiko Takeuchi0Masaya Iwamuro1Atsushi Imagawa2Yoshitsugu Kubota3Katsuya Miyatani4Katsuyoshi Takata5Hiroyuki Okada6Department of Gastroenterology, Mitoyo General Hospital, Kan'onji 769-1695, JapanDepartment of Gastroenterology, Mitoyo General Hospital, Kan'onji 769-1695, JapanDepartment of Gastroenterology, Mitoyo General Hospital, Kan'onji 769-1695, JapanDepartment of Transfusion Medicine, Faculty of Medicine, Kagawa University, Kita-Gun 761-0793, JapanDepartment of Pathology, Mitoyo General Hospital, Kan'onji 769-1695, JapanDepartment of Pathology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama 700-8558, JapanDepartment of Endoscopy, Okayama University Hospital, Okayama 700-8558, JapanA 52-year-old Japanese woman who was eventually diagnosed with primary follicular lymphoma of the duodenum showed atypical endoscopic features, namely, erosions with peripheral whitish edematous mucosa. Initial biopsy specimens taken from the erosions revealed insufficient numbers of lymphoma cells for histological diagnosis. Subsequent biopsy specimens from the peripheral mucosa containing the whitish enlarged villi showed infiltration of the lymphoma cells forming lymphoid follicles, which led us to the appropriate diagnosis. This case indicates that endoscopists should take biopsy samples from the peripheral mucosa with whitish enlarged villi rather than erosions in the rare instances that erosions appear as the main macroscopic feature of intestinal follicular lymphoma.http://dx.doi.org/10.1155/2012/582607
spellingShingle Keiko Takeuchi
Masaya Iwamuro
Atsushi Imagawa
Yoshitsugu Kubota
Katsuya Miyatani
Katsuyoshi Takata
Hiroyuki Okada
Primary Follicular Lymphoma of the Duodenum with Erosions as Atypical Macroscopic Features
Case Reports in Medicine
title Primary Follicular Lymphoma of the Duodenum with Erosions as Atypical Macroscopic Features
title_full Primary Follicular Lymphoma of the Duodenum with Erosions as Atypical Macroscopic Features
title_fullStr Primary Follicular Lymphoma of the Duodenum with Erosions as Atypical Macroscopic Features
title_full_unstemmed Primary Follicular Lymphoma of the Duodenum with Erosions as Atypical Macroscopic Features
title_short Primary Follicular Lymphoma of the Duodenum with Erosions as Atypical Macroscopic Features
title_sort primary follicular lymphoma of the duodenum with erosions as atypical macroscopic features
url http://dx.doi.org/10.1155/2012/582607
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