Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory molecules
Phytochemicals, the bioactive compounds derived from plants, play a significant role in modulating pathways leading to cancer and inflammation, rendering themselves promising candidates for therapeutic interventions. This review explores the multifaceted potential of various phytochemicals in modula...
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| Format: | Article |
| Language: | English |
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Open Exploration
2024-10-01
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| Series: | Exploration of Drug Science |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A100873/100873.pdf |
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| author | Shifana C. Sadiq Maria Pellissery Joy Sreekumar U. Aiswarya Abhishek Ajmani Chenicheri K. Keerthana Tennyson P. Rayginia Noah Isakov Ruby John Anto |
| author_facet | Shifana C. Sadiq Maria Pellissery Joy Sreekumar U. Aiswarya Abhishek Ajmani Chenicheri K. Keerthana Tennyson P. Rayginia Noah Isakov Ruby John Anto |
| author_sort | Shifana C. Sadiq |
| collection | DOAJ |
| description | Phytochemicals, the bioactive compounds derived from plants, play a significant role in modulating pathways leading to cancer and inflammation, rendering themselves promising candidates for therapeutic interventions. This review explores the multifaceted potential of various phytochemicals in modulating key mechanisms involved in the development and progression of cancer and inflammation. The diverse array of phytochemicals discussed here encompasses polyphenols, flavonoids, alkaloids, terpenoids, and many others, each with distinct molecular targets and modes of action. This review is an attempt to elucidate and correlate the regulatory role of phytochemicals on cellular signaling pathways implicated in oncogenesis and inflammatory responses, highlighting the significance and potential of phytochemical-based therapies for cancer prevention and treatment, as well as for managing inflammatory conditions. By exploring the promising potential of phytochemical-based remedies for cancer prevention, treatment, and inflammatory conditions and emphasizing their diverse roles in modulating critical regulatory mechanisms, this review addresses the current research landscape, challenges, and future directions in utilizing phytochemicals as effective agents against cancer and inflammation. |
| format | Article |
| id | doaj-art-53a2407fa02c458696d87fa74daeeed7 |
| institution | Kabale University |
| issn | 2836-7677 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Open Exploration |
| record_format | Article |
| series | Exploration of Drug Science |
| spelling | doaj-art-53a2407fa02c458696d87fa74daeeed72025-02-08T03:28:18ZengOpen ExplorationExploration of Drug Science2836-76772024-10-012674478410.37349/eds.2024.00073Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory moleculesShifana C. Sadiq0Maria Pellissery Joy1Sreekumar U. Aiswarya2Abhishek Ajmani3Chenicheri K. Keerthana4Tennyson P. Rayginia5Noah Isakov6https://orcid.org/0000-0002-1412-0957Ruby John Anto7https://orcid.org/0000-0001-5856-0076Molecular Bioassay Laboratory, Institute of Advanced Virology, Thiruvananthapuram 695317, Kerala, India; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, IndiaDivision of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, IndiaDivision of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, IndiaMolecular Bioassay Laboratory, Institute of Advanced Virology, Thiruvananthapuram 695317, Kerala, IndiaDivision of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, IndiaMolecular Bioassay Laboratory, Institute of Advanced Virology, Thiruvananthapuram 695317, Kerala, India; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, IndiaThe Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, IsraelMolecular Bioassay Laboratory, Institute of Advanced Virology, Thiruvananthapuram 695317, Kerala, India; Division of Cancer Research, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram 695014, Kerala, India; Centre of Excellence in Nutraceuticals, KSCSTE, Government of Kerala, Thiruvananthapuram 695317, Kerala, IndiaPhytochemicals, the bioactive compounds derived from plants, play a significant role in modulating pathways leading to cancer and inflammation, rendering themselves promising candidates for therapeutic interventions. This review explores the multifaceted potential of various phytochemicals in modulating key mechanisms involved in the development and progression of cancer and inflammation. The diverse array of phytochemicals discussed here encompasses polyphenols, flavonoids, alkaloids, terpenoids, and many others, each with distinct molecular targets and modes of action. This review is an attempt to elucidate and correlate the regulatory role of phytochemicals on cellular signaling pathways implicated in oncogenesis and inflammatory responses, highlighting the significance and potential of phytochemical-based therapies for cancer prevention and treatment, as well as for managing inflammatory conditions. By exploring the promising potential of phytochemical-based remedies for cancer prevention, treatment, and inflammatory conditions and emphasizing their diverse roles in modulating critical regulatory mechanisms, this review addresses the current research landscape, challenges, and future directions in utilizing phytochemicals as effective agents against cancer and inflammation.https://www.explorationpub.com/uploads/Article/A100873/100873.pdfphytochemicalscancerinflammationoncogenic pathwayschemoprevention |
| spellingShingle | Shifana C. Sadiq Maria Pellissery Joy Sreekumar U. Aiswarya Abhishek Ajmani Chenicheri K. Keerthana Tennyson P. Rayginia Noah Isakov Ruby John Anto Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory molecules Exploration of Drug Science phytochemicals cancer inflammation oncogenic pathways chemoprevention |
| title | Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory molecules |
| title_full | Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory molecules |
| title_fullStr | Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory molecules |
| title_full_unstemmed | Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory molecules |
| title_short | Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory molecules |
| title_sort | unlocking nature s pharmacy an in depth exploration of phytochemicals as potential sources of anti cancer and anti inflammatory molecules |
| topic | phytochemicals cancer inflammation oncogenic pathways chemoprevention |
| url | https://www.explorationpub.com/uploads/Article/A100873/100873.pdf |
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