(Apo)Lipoprotein Profiling with Multi‐Omics Analysis Identified Medium‐HDL‐Targeting PSRC1 with Therapeutic Potential for Coronary Artery Disease

(Apo)Lipoprotein Profiling with Multi‐Omics Analysis Identified Medium‐HDL‐Targeting PSRC1 with Therapeutic Potential for Coronary Artery Disease

Abstract Identification of (apo)lipoprotein subclasses causally underpinning atherosclerosis may lead to identification of novel drug targets for treatment of atherosclerotic cardiovascular disease (ASCVD). In this study, observational and genetic associations between (apo)lipoprotein profile and ca...

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Bibliographic Details
Main Authors: Yingmei Li, Sihan Wang, Ling Liu, Hao Cai, Yacan Huang, Mingjing Gao, Xiaogang Zhang, Qingqing Wu, Gaokun Qiu
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
(apo)lipoprotein profiling
atherosclerotic cardiovascular disease
carotid intima‐media thickness
colocalization
mendelian randomization
multi‐omics
Online Access:https://doi.org/10.1002/advs.202413491
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