Spontaneous granulation of tricaprin and trilaurin medium-chain triacylglycerols with added medium- and long-chain species

Abstract To utilize medium-chain triacylglycerol (MCT) with a low smoke point (~150 °C) in water, we investigated formulations and physical conditions for its spontaneous powdery crystallization without excipients. Crystallization of tricaprin and trilaurin mixed with medium- and long-chain triacylg...

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Bibliographic Details
Main Authors: Yutaro Kataoka, Hidetaka Uehara, Kentaro Matsumiya
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Science of Food
Online Access:https://doi.org/10.1038/s41538-025-00511-x
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Summary:Abstract To utilize medium-chain triacylglycerol (MCT) with a low smoke point (~150 °C) in water, we investigated formulations and physical conditions for its spontaneous powdery crystallization without excipients. Crystallization of tricaprin and trilaurin mixed with medium- and long-chain triacylglycerols (MLCT) at varying ratios and temperatures was observed. Both oils mixed spontaneously crystallized into powder below their solidification temperature, structuring micrometer-ordered stacked plate crystals. Differential scanning calorimetry and X-ray diffraction measurements showed stable β−form polymorphism. Steric effects from the MLCT hindered fat crystal network formation, promoting lamellar structures that easily broke into porous crystals. Thermal energy and the van der Waals forces indicated that the excess carbon chains biased the horizontal development of the lamellar structures. The resulting powder had a finer particle size and increased bulkiness than commercial products. The tricaprin-based powder was wettable, forming a paste with water, while the trilaurin-based powder was not, making the tricaprin-based powder more suitable for food applications.
ISSN:2396-8370