Clinical Efficacy of Percutaneous Kyphoplasty Combined with Calcitriol and Calcium in the Treatment of Traumatic Nonosteoporotic Vertebral Compression Fractures

Objective. The present study investigated the clinical efficacy of percutaneous kyphoplasty (PKP) combined with calcitriol and calcium in the treatment of traumatic nonosteoporotic vertebral compression fractures (TNVCFs). Methods. The patients were equally divided into a control group and a treatme...

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Main Authors: Shouqian Dai, Xin Lu, Ningning Dai, Xiu Shi, Peng Yang, Peng Peng, Feng Xu
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2022/3489160
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author Shouqian Dai
Xin Lu
Ningning Dai
Xiu Shi
Peng Yang
Peng Peng
Feng Xu
author_facet Shouqian Dai
Xin Lu
Ningning Dai
Xiu Shi
Peng Yang
Peng Peng
Feng Xu
author_sort Shouqian Dai
collection DOAJ
description Objective. The present study investigated the clinical efficacy of percutaneous kyphoplasty (PKP) combined with calcitriol and calcium in the treatment of traumatic nonosteoporotic vertebral compression fractures (TNVCFs). Methods. The patients were equally divided into a control group and a treatment group by a random number table. The patients in the control group underwent PKP surgery, and the patients in the treatment group received calcitriol and calcium on the basis of PKP surgery. The visual analog scale (VAS) pain scores, Oswestry Disability Index (ODI) scores, the height of the anterior edge of the vertebral body, Cobb’s angle, and the level of the bone mineral density of the two groups of TNVCF patients before surgery were recorded and compared, one and six months after surgery. Results. Thirty-six inpatients with TNVCFs admitted to the trauma center of the First Affiliated Hospital of Soochow University from January 2019 to January 2020 were recruited. There were no significant differences in the VAS and ODI scores, the height of the anterior edge of the injured vertebral body, Cobb’s angle, and bone mineral density between the two groups before surgery (P>0.05). The VAS scores, ODI scores, the height of the anterior edge of the injured vertebral body, and Cobb’s angle of the two groups of patients after surgery were significantly better than those before surgery. One and six months after surgery, the VAS and ODI scores, the height of the anterior edge of the injured vertebral body, Cobb’s angle, and the bone mineral density of the patients in the treatment group improved significantly compared to those in the control group (P<0.05). Conclusions. PKP combined with calcitriol and calcium medications could significantly relieve pain, alleviate the loss of compressed vertebral height and kyphosis, and improve the spinal function and the life quality of the TNVCF patients.
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spelling doaj-art-537b9ba7a3ae48cc8602e0b7144b94d62025-02-03T00:59:54ZengWileyPain Research and Management1918-15232022-01-01202210.1155/2022/3489160Clinical Efficacy of Percutaneous Kyphoplasty Combined with Calcitriol and Calcium in the Treatment of Traumatic Nonosteoporotic Vertebral Compression FracturesShouqian Dai0Xin Lu1Ningning Dai2Xiu Shi3Peng Yang4Peng Peng5Feng Xu6Department of Emergency MedicineDepartment of Emergency MedicineDepartment of Emergency MedicineDepartment of Obstetrics and GynecologyDepartment of Emergency MedicineDepartment of Emergency MedicineDepartment of Emergency MedicineObjective. The present study investigated the clinical efficacy of percutaneous kyphoplasty (PKP) combined with calcitriol and calcium in the treatment of traumatic nonosteoporotic vertebral compression fractures (TNVCFs). Methods. The patients were equally divided into a control group and a treatment group by a random number table. The patients in the control group underwent PKP surgery, and the patients in the treatment group received calcitriol and calcium on the basis of PKP surgery. The visual analog scale (VAS) pain scores, Oswestry Disability Index (ODI) scores, the height of the anterior edge of the vertebral body, Cobb’s angle, and the level of the bone mineral density of the two groups of TNVCF patients before surgery were recorded and compared, one and six months after surgery. Results. Thirty-six inpatients with TNVCFs admitted to the trauma center of the First Affiliated Hospital of Soochow University from January 2019 to January 2020 were recruited. There were no significant differences in the VAS and ODI scores, the height of the anterior edge of the injured vertebral body, Cobb’s angle, and bone mineral density between the two groups before surgery (P>0.05). The VAS scores, ODI scores, the height of the anterior edge of the injured vertebral body, and Cobb’s angle of the two groups of patients after surgery were significantly better than those before surgery. One and six months after surgery, the VAS and ODI scores, the height of the anterior edge of the injured vertebral body, Cobb’s angle, and the bone mineral density of the patients in the treatment group improved significantly compared to those in the control group (P<0.05). Conclusions. PKP combined with calcitriol and calcium medications could significantly relieve pain, alleviate the loss of compressed vertebral height and kyphosis, and improve the spinal function and the life quality of the TNVCF patients.http://dx.doi.org/10.1155/2022/3489160
spellingShingle Shouqian Dai
Xin Lu
Ningning Dai
Xiu Shi
Peng Yang
Peng Peng
Feng Xu
Clinical Efficacy of Percutaneous Kyphoplasty Combined with Calcitriol and Calcium in the Treatment of Traumatic Nonosteoporotic Vertebral Compression Fractures
Pain Research and Management
title Clinical Efficacy of Percutaneous Kyphoplasty Combined with Calcitriol and Calcium in the Treatment of Traumatic Nonosteoporotic Vertebral Compression Fractures
title_full Clinical Efficacy of Percutaneous Kyphoplasty Combined with Calcitriol and Calcium in the Treatment of Traumatic Nonosteoporotic Vertebral Compression Fractures
title_fullStr Clinical Efficacy of Percutaneous Kyphoplasty Combined with Calcitriol and Calcium in the Treatment of Traumatic Nonosteoporotic Vertebral Compression Fractures
title_full_unstemmed Clinical Efficacy of Percutaneous Kyphoplasty Combined with Calcitriol and Calcium in the Treatment of Traumatic Nonosteoporotic Vertebral Compression Fractures
title_short Clinical Efficacy of Percutaneous Kyphoplasty Combined with Calcitriol and Calcium in the Treatment of Traumatic Nonosteoporotic Vertebral Compression Fractures
title_sort clinical efficacy of percutaneous kyphoplasty combined with calcitriol and calcium in the treatment of traumatic nonosteoporotic vertebral compression fractures
url http://dx.doi.org/10.1155/2022/3489160
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