Effectiveness, cost-effectiveness and safety of gabapentin versus placebo as an adjunct to multimodal pain regimens in surgical patients: protocol of a placebo controlled randomised controlled trial with blinding (GAP study)

Effectiveness, cost-effectiveness and safety of gabapentin versus placebo as an adjunct to multimodal pain regimens in surgical patients: protocol of a placebo controlled randomised controlled trial with blinding (GAP study)

Introduction Gabapentin is an antiepileptic drug currently licensed to treat epilepsy and neuropathic pain but has been used off-label to treat acute postoperative pain. The GAP study will compare the effectiveness, cost-effectiveness and safety of gabapentin as an adjunct to standard multimodal ana...

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Main Authors: Chris A Rogers, Lucy Culliford, Maria Pufulete, Sarah Baos, Mark Edwards, Sarah Wordsworth, Elizabeth A Stokes, Holly Mckeon, Gianluca Casali, Aiman Alzetani, Reyad Abbadi, Nilesh Chauhan, Laura Collett, Samantha E de Jesus, Nicholas Goddard, Jennifer Lamb, Mat Molyneux, Ben Gibbison
Format: Article
Language:English
Published: BMJ Publishing Group 2020-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/11/e041176.full
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