Transcriptional profiling of immune responses in NHPs after low-dose, VSV-based vaccination against Marburg virus

Transcriptional profiling of immune responses in NHPs after low-dose, VSV-based vaccination against Marburg virus

Infection with Marburg virus (MARV), the causative agent of Marburg virus disease (MVD), results in haemorrhagic disease and high case fatality rates (>40%) in humans. Despite its public health relevance, there are no licensed vaccines or therapeutics to prevent or treat MVD. A vesicular stomatit...

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Bibliographic Details
Main Authors: Cecilia A. Prator, Brianna M. Dorratt, Kyle L. O’Donnell, Justin Lack, Amanda N. Pinski, Stacy Ricklefs, Craig A. Martens, Ilhem Messaoudi, Andrea Marzi
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
Filovirus
Marburg virus Angola
MARV
vesicular stomatitis virus
nonhuman primate
host response
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2252513
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