Research Progress on Phytochemicals from Mulberry with Neuroprotective Effects: A Review
With the intensification of the population aging worldwide, neurological disorders (NDs) are seriously threatening human society. Mulberry, a traditional economic crop, is a significant medicinal plant. Increasing evidence suggests that phytochemicals from mulberry play critical roles in the prevent...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Pharmaceuticals |
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| Online Access: | https://www.mdpi.com/1424-8247/18/5/695 |
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| author | Junwei Chen Zhonglang Gou Yufei Huang Qianhui Yu An Na Kim Wenchao Shi You Zhou |
| author_facet | Junwei Chen Zhonglang Gou Yufei Huang Qianhui Yu An Na Kim Wenchao Shi You Zhou |
| author_sort | Junwei Chen |
| collection | DOAJ |
| description | With the intensification of the population aging worldwide, neurological disorders (NDs) are seriously threatening human society. Mulberry, a traditional economic crop, is a significant medicinal plant. Increasing evidence suggests that phytochemicals from mulberry play critical roles in the prevention and treatment of NDs. This paper reviews the recently reported phytochemicals from mulberry with neuroprotective effects and systematically summarizes neuroprotective mechanisms and their classifications. Based on their origins from different parts of mulberry, the extracts with neuroprotective effects are classified into mulberry fruit extract and mulberry leaf extract. According to the compound structures, the compounds are divided into flavonoids, Diels–Alder-type adducts (DAAs), benzofurans, quinones, stilbenes, and alkaloids. This aims to provide a future reference for their pharmaceutical development and utilization. |
| format | Article |
| id | doaj-art-5371688702ef4e07aaab81b5d2532f13 |
| institution | Kabale University |
| issn | 1424-8247 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj-art-5371688702ef4e07aaab81b5d2532f132025-08-20T03:48:01ZengMDPI AGPharmaceuticals1424-82472025-05-0118569510.3390/ph18050695Research Progress on Phytochemicals from Mulberry with Neuroprotective Effects: A ReviewJunwei Chen0Zhonglang Gou1Yufei Huang2Qianhui Yu3An Na Kim4Wenchao Shi5You Zhou6State Key Laboratory of Resource Insects, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaState Key Laboratory of Resource Insects, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaWesta College, Southwest University, Chongqing 400715, ChinaWesta College, Southwest University, Chongqing 400715, ChinaCDD Engine, Lino Lakes, MN 55014, USAState Key Laboratory of Resource Insects, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaState Key Laboratory of Resource Insects, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaWith the intensification of the population aging worldwide, neurological disorders (NDs) are seriously threatening human society. Mulberry, a traditional economic crop, is a significant medicinal plant. Increasing evidence suggests that phytochemicals from mulberry play critical roles in the prevention and treatment of NDs. This paper reviews the recently reported phytochemicals from mulberry with neuroprotective effects and systematically summarizes neuroprotective mechanisms and their classifications. Based on their origins from different parts of mulberry, the extracts with neuroprotective effects are classified into mulberry fruit extract and mulberry leaf extract. According to the compound structures, the compounds are divided into flavonoids, Diels–Alder-type adducts (DAAs), benzofurans, quinones, stilbenes, and alkaloids. This aims to provide a future reference for their pharmaceutical development and utilization.https://www.mdpi.com/1424-8247/18/5/695mulberryneurological disordersphytochemicalsneuroprotection |
| spellingShingle | Junwei Chen Zhonglang Gou Yufei Huang Qianhui Yu An Na Kim Wenchao Shi You Zhou Research Progress on Phytochemicals from Mulberry with Neuroprotective Effects: A Review Pharmaceuticals mulberry neurological disorders phytochemicals neuroprotection |
| title | Research Progress on Phytochemicals from Mulberry with Neuroprotective Effects: A Review |
| title_full | Research Progress on Phytochemicals from Mulberry with Neuroprotective Effects: A Review |
| title_fullStr | Research Progress on Phytochemicals from Mulberry with Neuroprotective Effects: A Review |
| title_full_unstemmed | Research Progress on Phytochemicals from Mulberry with Neuroprotective Effects: A Review |
| title_short | Research Progress on Phytochemicals from Mulberry with Neuroprotective Effects: A Review |
| title_sort | research progress on phytochemicals from mulberry with neuroprotective effects a review |
| topic | mulberry neurological disorders phytochemicals neuroprotection |
| url | https://www.mdpi.com/1424-8247/18/5/695 |
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