Automated and virus variant-programmable surrogate test qualitatively compares to the gold standard SARS-CoV-2 neutralization assay

Automated and virus variant-programmable surrogate test qualitatively compares to the gold standard SARS-CoV-2 neutralization assay

Abstract The ongoing emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants underscores the need for rapid, adaptable, high-throughput testing. However, assays for neutralizing antibodies, which are a good measure of viral protection, usually require cell culture and...

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Main Authors: Danielle W. Ali, Maggie L. Bartlett, Christopher D. Heger, Francisco Ramirez, Linwood Johnson, Kevin L. Schully, Eric D. Laing, Wei Wang, Carol D. Weiss, Emilie Goguet, Christopher C. Broder, Stephanie A. Richard, Nusrat J. Epsi, Brian Agan, David Tribble, Mark P. Simons, Timothy H. Burgess, Edward Mitre, Simon Pollett, Darci R. Smith
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:npj Viruses
Online Access:https://doi.org/10.1038/s44298-024-00083-9
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