The Power of CRISPR-Cas9-Induced Genome Editing to Speed Up Plant Breeding

Genome editing with engineered nucleases enabling site-directed sequence modifications bears a great potential for advanced plant breeding and crop protection. Remarkably, the RNA-guided endonuclease technology (RGEN) based on the clustered regularly interspaced short palindromic repeats (CRISPR) an...

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Bibliographic Details
Main Authors: Hieu X. Cao, Wenqin Wang, Hien T. T. Le, Giang T. H. Vu
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:International Journal of Genomics
Online Access:http://dx.doi.org/10.1155/2016/5078796
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Summary:Genome editing with engineered nucleases enabling site-directed sequence modifications bears a great potential for advanced plant breeding and crop protection. Remarkably, the RNA-guided endonuclease technology (RGEN) based on the clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein 9 (Cas9) is an extremely powerful and easy tool that revolutionizes both basic research and plant breeding. Here, we review the major technical advances and recent applications of the CRISPR-Cas9 system for manipulation of model and crop plant genomes. We also discuss the future prospects of this technology in molecular plant breeding.
ISSN:2314-436X
2314-4378