Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers

End stage renal disease is a relatively frequent disease with high mortality due to cardiac causes. Permanent pacemaker (PM) implantation rates are also very common; thus combination of both conditions is not unusual. We hypothesized that patients with chronic kidney disease with a PM would have sig...

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Main Authors: Gabriel Vanerio, Cristina García, Carlota González, Alejandro Ferreiro
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:International Journal of Nephrology
Online Access:http://dx.doi.org/10.1155/2014/284172
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author Gabriel Vanerio
Cristina García
Carlota González
Alejandro Ferreiro
author_facet Gabriel Vanerio
Cristina García
Carlota González
Alejandro Ferreiro
author_sort Gabriel Vanerio
collection DOAJ
description End stage renal disease is a relatively frequent disease with high mortality due to cardiac causes. Permanent pacemaker (PM) implantation rates are also very common; thus combination of both conditions is not unusual. We hypothesized that patients with chronic kidney disease with a PM would have significantly higher mortality rates compared with end stage renal disease patients without PM. Our objectives were to analyze mortality of patients on renal replacement therapy with PM. 2778 patients were on renal replacement therapy (RRT) and 110 had a PM implanted during the study period. To reduce the confounding effects of covariates, a propensity-matched score was performed. 52 PM patients and 208 non-PM matched patients were compared. 41% of the PM were implanted before entering the RRT program and 59% while on RRT. Mortality was higher in the PM group. Cardiovascular disease and infections were the most frequent causes of death. Propensity analysis showed no differences in long-term mortality between groups. We concluded that in patients on RRT and PM mortality rates are higher. Survival curves did not differ from a RRT propensity-matched group. We concluded that the presence of a PM is not an independent mortality risk factor in RRT patients.
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spelling doaj-art-534fbd2f820444bdbe19ad3ca5c43a4d2025-08-20T02:05:32ZengWileyInternational Journal of Nephrology2090-214X2090-21582014-01-01201410.1155/2014/284172284172Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac PacemakersGabriel Vanerio0Cristina García1Carlota González2Alejandro Ferreiro3CASMU Arrhythmia Service, 8 de Octubre 3310, 11600 Montevideo, UruguayCASMU Arrhythmia Service, 8 de Octubre 3310, 11600 Montevideo, UruguayCASMU Arrhythmia Service, 8 de Octubre 3310, 11600 Montevideo, UruguayCASMU Arrhythmia Service, 8 de Octubre 3310, 11600 Montevideo, UruguayEnd stage renal disease is a relatively frequent disease with high mortality due to cardiac causes. Permanent pacemaker (PM) implantation rates are also very common; thus combination of both conditions is not unusual. We hypothesized that patients with chronic kidney disease with a PM would have significantly higher mortality rates compared with end stage renal disease patients without PM. Our objectives were to analyze mortality of patients on renal replacement therapy with PM. 2778 patients were on renal replacement therapy (RRT) and 110 had a PM implanted during the study period. To reduce the confounding effects of covariates, a propensity-matched score was performed. 52 PM patients and 208 non-PM matched patients were compared. 41% of the PM were implanted before entering the RRT program and 59% while on RRT. Mortality was higher in the PM group. Cardiovascular disease and infections were the most frequent causes of death. Propensity analysis showed no differences in long-term mortality between groups. We concluded that in patients on RRT and PM mortality rates are higher. Survival curves did not differ from a RRT propensity-matched group. We concluded that the presence of a PM is not an independent mortality risk factor in RRT patients.http://dx.doi.org/10.1155/2014/284172
spellingShingle Gabriel Vanerio
Cristina García
Carlota González
Alejandro Ferreiro
Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
International Journal of Nephrology
title Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_full Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_fullStr Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_full_unstemmed Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_short Mortality in Patients on Renal Replacement Therapy and Permanent Cardiac Pacemakers
title_sort mortality in patients on renal replacement therapy and permanent cardiac pacemakers
url http://dx.doi.org/10.1155/2014/284172
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AT carlotagonzalez mortalityinpatientsonrenalreplacementtherapyandpermanentcardiacpacemakers
AT alejandroferreiro mortalityinpatientsonrenalreplacementtherapyandpermanentcardiacpacemakers