Synchronous Malignant Peripheral Nerve Sheath Tumor and Adenocarcinoma of the Prostate: Case Report and Literature Review

Malignant Peripheral Nerve Sheath Tumors (MPNSTs) of the prostate are extremely rare. A very unusual case of simultaneous adenocarcinoma and MPNST of the prostate is reported. A 60-year-old Caucasian male presented for annual urologic examination. Digital rectal examination revealed a painless, toug...

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Main Authors: Nikolaos Ferakis, Antonios Katsimantas, Konstantinos Bouropoulos, Antonios Farmakis
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2016/2457416
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author Nikolaos Ferakis
Antonios Katsimantas
Konstantinos Bouropoulos
Antonios Farmakis
author_facet Nikolaos Ferakis
Antonios Katsimantas
Konstantinos Bouropoulos
Antonios Farmakis
author_sort Nikolaos Ferakis
collection DOAJ
description Malignant Peripheral Nerve Sheath Tumors (MPNSTs) of the prostate are extremely rare. A very unusual case of simultaneous adenocarcinoma and MPNST of the prostate is reported. A 60-year-old Caucasian male presented for annual urologic examination. Digital rectal examination revealed a painless, toughish, and asymmetrically enlarged prostate. Serum prostate-specific antigen was 1 ng/mL. Radiologic examinations demonstrated a large mass, which was arising from the left peripheral lobe of the prostate. The patient underwent transrectal ultrasound-guided biopsy of the prostate which revealed a smooth muscle tumor of uncertain malignant potential. Radical retropubic prostatectomy with en bloc removal of the mass and the seminal vesicles was performed and histology demonstrated low-grade MPNST and adenocarcinoma of the prostate. To the best of our knowledge, this is the first report of simultaneous prostatic adenocarcinoma and MPNST in the English literature.
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issn 2090-696X
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series Case Reports in Urology
spelling doaj-art-533a6dc4c87243ab9f5bbb82e98b21712025-08-20T03:36:42ZengWileyCase Reports in Urology2090-696X2090-69782016-01-01201610.1155/2016/24574162457416Synchronous Malignant Peripheral Nerve Sheath Tumor and Adenocarcinoma of the Prostate: Case Report and Literature ReviewNikolaos Ferakis0Antonios Katsimantas1Konstantinos Bouropoulos2Antonios Farmakis3Department of Urology, Korgialenio-Benakio Hellenic Red Cross Hospital, Athanasaki 1, 115 26 Athens, GreeceDepartment of Urology, Korgialenio-Benakio Hellenic Red Cross Hospital, Athanasaki 1, 115 26 Athens, GreeceDepartment of Urology, Korgialenio-Benakio Hellenic Red Cross Hospital, Athanasaki 1, 115 26 Athens, GreeceDepartment of Urology, Korgialenio-Benakio Hellenic Red Cross Hospital, Athanasaki 1, 115 26 Athens, GreeceMalignant Peripheral Nerve Sheath Tumors (MPNSTs) of the prostate are extremely rare. A very unusual case of simultaneous adenocarcinoma and MPNST of the prostate is reported. A 60-year-old Caucasian male presented for annual urologic examination. Digital rectal examination revealed a painless, toughish, and asymmetrically enlarged prostate. Serum prostate-specific antigen was 1 ng/mL. Radiologic examinations demonstrated a large mass, which was arising from the left peripheral lobe of the prostate. The patient underwent transrectal ultrasound-guided biopsy of the prostate which revealed a smooth muscle tumor of uncertain malignant potential. Radical retropubic prostatectomy with en bloc removal of the mass and the seminal vesicles was performed and histology demonstrated low-grade MPNST and adenocarcinoma of the prostate. To the best of our knowledge, this is the first report of simultaneous prostatic adenocarcinoma and MPNST in the English literature.http://dx.doi.org/10.1155/2016/2457416
spellingShingle Nikolaos Ferakis
Antonios Katsimantas
Konstantinos Bouropoulos
Antonios Farmakis
Synchronous Malignant Peripheral Nerve Sheath Tumor and Adenocarcinoma of the Prostate: Case Report and Literature Review
Case Reports in Urology
title Synchronous Malignant Peripheral Nerve Sheath Tumor and Adenocarcinoma of the Prostate: Case Report and Literature Review
title_full Synchronous Malignant Peripheral Nerve Sheath Tumor and Adenocarcinoma of the Prostate: Case Report and Literature Review
title_fullStr Synchronous Malignant Peripheral Nerve Sheath Tumor and Adenocarcinoma of the Prostate: Case Report and Literature Review
title_full_unstemmed Synchronous Malignant Peripheral Nerve Sheath Tumor and Adenocarcinoma of the Prostate: Case Report and Literature Review
title_short Synchronous Malignant Peripheral Nerve Sheath Tumor and Adenocarcinoma of the Prostate: Case Report and Literature Review
title_sort synchronous malignant peripheral nerve sheath tumor and adenocarcinoma of the prostate case report and literature review
url http://dx.doi.org/10.1155/2016/2457416
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AT konstantinosbouropoulos synchronousmalignantperipheralnervesheathtumorandadenocarcinomaoftheprostatecasereportandliteraturereview
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