Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical Methods

Objective: to optimize preoperative preparation of patients with multifocal atherosclerosis and reduced baseline left ventricular ejection fraction for coronary bypass surgery, by providing a rationale for the use of mechanical and medical circulatory support methods. Subjects and methods. Sixty-one...

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Main Authors: E. V. Grigoryev, A. V. Geize, G. P. Plotnikov, I. N. Sizova, D. L. Shukevich, A. N. Sumin
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2011-12-01
Series:Общая реаниматология
Online Access:https://www.reanimatology.com/rmt/article/view/256
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author E. V. Grigoryev
A. V. Geize
G. P. Plotnikov
I. N. Sizova
D. L. Shukevich
A. N. Sumin
author_facet E. V. Grigoryev
A. V. Geize
G. P. Plotnikov
I. N. Sizova
D. L. Shukevich
A. N. Sumin
author_sort E. V. Grigoryev
collection DOAJ
description Objective: to optimize preoperative preparation of patients with multifocal atherosclerosis and reduced baseline left ventricular ejection fraction for coronary bypass surgery, by providing a rationale for the use of mechanical and medical circulatory support methods. Subjects and methods. Sixty-one patients with multifocal atherosclerosis, coronary heart disease (CHD), and reduced baseline left ventricular ejection fraction, who underwent coronary bypass surgery, were examined. Levosimendan was administered to 2 groups of patients: 1) 28 patients with preoperative intra-aortic balloon counterpulsation; 2) as inotropic support in 33 patients. There were central and intracardiac hemodynamic changes as evidenced by transpulmonary thermodilution and pulsed Doppler ultrasound echocardiog-raphy during different preoperative preparations. Conclusion. The use of levosimendan in patients with multifocal atherosclerosis, CHD, and planned coronary bypass surgery, by taking into account contraindications to intra-aor-tic balloon counterpulsation, makes it possible to improve central hemodynamical parameters and to reduce the degree of diastolic dysfunction, the incidence of organ dysfunctions, and the length of intensive care unit stay. Key words: coronary bypass surgery, left ventricular ejection fraction, multifocal atherosclerosis, levosimendan, intra-aortic balloon counterpulsation.
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spelling doaj-art-5338cd2e40bb4b3cbf9884592141f35e2025-08-20T02:55:49ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102011-12-017610.15360/1813-9779-2011-6-53256Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical MethodsE. V. GrigoryevA. V. GeizeG. P. PlotnikovI. N. SizovaD. L. ShukevichA. N. SuminObjective: to optimize preoperative preparation of patients with multifocal atherosclerosis and reduced baseline left ventricular ejection fraction for coronary bypass surgery, by providing a rationale for the use of mechanical and medical circulatory support methods. Subjects and methods. Sixty-one patients with multifocal atherosclerosis, coronary heart disease (CHD), and reduced baseline left ventricular ejection fraction, who underwent coronary bypass surgery, were examined. Levosimendan was administered to 2 groups of patients: 1) 28 patients with preoperative intra-aortic balloon counterpulsation; 2) as inotropic support in 33 patients. There were central and intracardiac hemodynamic changes as evidenced by transpulmonary thermodilution and pulsed Doppler ultrasound echocardiog-raphy during different preoperative preparations. Conclusion. The use of levosimendan in patients with multifocal atherosclerosis, CHD, and planned coronary bypass surgery, by taking into account contraindications to intra-aor-tic balloon counterpulsation, makes it possible to improve central hemodynamical parameters and to reduce the degree of diastolic dysfunction, the incidence of organ dysfunctions, and the length of intensive care unit stay. Key words: coronary bypass surgery, left ventricular ejection fraction, multifocal atherosclerosis, levosimendan, intra-aortic balloon counterpulsation.https://www.reanimatology.com/rmt/article/view/256
spellingShingle E. V. Grigoryev
A. V. Geize
G. P. Plotnikov
I. N. Sizova
D. L. Shukevich
A. N. Sumin
Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical Methods
Общая реаниматология
title Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical Methods
title_full Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical Methods
title_fullStr Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical Methods
title_full_unstemmed Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical Methods
title_short Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical Methods
title_sort preoperative preparation of patients with multifocal atherosclerosis for coronary bypass surgery mechanical and medical methods
url https://www.reanimatology.com/rmt/article/view/256
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