Thermal insight to magnetized tri hybrid nanofluid (CuO-TiO2-SiO2)/blood with nonlinear radiated Effects: Applications to hyperthermia cancer treatment

The tri hybrid nanofluids are modified class of nanomaterials with efficient heat transfer performances, conveying novel applications in advanced energy systems, heat exchangers and solar thermal collectors. Subject to biocompatible blood-based formulations, recently, the scientists have claimed the...

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Main Authors: Mohamed Arbi Khlifi, Faisal Mahroogi, Iskander Tlili
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Case Studies in Thermal Engineering
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214157X25004952
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author Mohamed Arbi Khlifi
Faisal Mahroogi
Iskander Tlili
author_facet Mohamed Arbi Khlifi
Faisal Mahroogi
Iskander Tlili
author_sort Mohamed Arbi Khlifi
collection DOAJ
description The tri hybrid nanofluids are modified class of nanomaterials with efficient heat transfer performances, conveying novel applications in advanced energy systems, heat exchangers and solar thermal collectors. Subject to biocompatible blood-based formulations, recently, the scientists have claimed the applications of such materials in the hyperthermia cancer treatments and targeted thermal therapies. Owing to such prestigious and motivated applications of tri hybrid nanofluids, the objective of current analysis is to presents biomedical applications of magnetized tri nanoparticles subject to human blood. Tri hybrid nanofluid thermal properties are endorsed by utilizing three different nanoparticles copper oxide (CuO), titanium oxide (TiO2), and silicon oxide (SiO2) with blood base material. The flow problem is incorporating the modified thermal theories. The rheological characteristics of human blood are justified by using the Casson fluid model. The thermal results are further supported with nonlinear radiated model and heat generation applications. More realistic convective thermal constraints for inspection of thermal simulations. After expressing the governing model in nonlinear differential equations, the numerical computations are performed via shooting scheme. The relative comparative thermal performances current model is examined for mono nanofluid TiO2/blood, hybrid nanoparticles CuO−TiO2/blood and tri-hybrid nanofluid TiO2−CuO−SiO2/blood. It has been predicted that enhancement in nanoparticles volume fraction increases the thermal phenomenon and heat transfer characteristics. In contrast, increment in Prandtl number and relaxation time parameter controls the heat transfer efficiency, indicating thermal resistance with tri hybrid nanofluid. Furthermore, thermal performance of tri nanofluid is more efficient as compared to mono and hybrid nanofluids. The simulated findings preserve significance in biomedical applications, especially in improving the drug delivery systems and enhancing thermal managements in hyperthermia treatments.
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spelling doaj-art-53367b6966464e8699ae94d6bb45b7422025-08-20T03:52:47ZengElsevierCase Studies in Thermal Engineering2214-157X2025-08-017210623510.1016/j.csite.2025.106235Thermal insight to magnetized tri hybrid nanofluid (CuO-TiO2-SiO2)/blood with nonlinear radiated Effects: Applications to hyperthermia cancer treatmentMohamed Arbi Khlifi0Faisal Mahroogi1Iskander Tlili2Department of Electrical Engineering, Faculty of Engineering, Islamic University of Madinah, Madinah, 42351, Saudi ArabiaDepartment of Mechanical Engineering, Faculty of Engineering, Islamic University of Madinah, Madinah, 42351, Saudi ArabiaDepartment of Mechanical Engineering, Faculty of Engineering, Islamic University of Madinah, Madinah, 42351, Saudi Arabia; Corresponding author.The tri hybrid nanofluids are modified class of nanomaterials with efficient heat transfer performances, conveying novel applications in advanced energy systems, heat exchangers and solar thermal collectors. Subject to biocompatible blood-based formulations, recently, the scientists have claimed the applications of such materials in the hyperthermia cancer treatments and targeted thermal therapies. Owing to such prestigious and motivated applications of tri hybrid nanofluids, the objective of current analysis is to presents biomedical applications of magnetized tri nanoparticles subject to human blood. Tri hybrid nanofluid thermal properties are endorsed by utilizing three different nanoparticles copper oxide (CuO), titanium oxide (TiO2), and silicon oxide (SiO2) with blood base material. The flow problem is incorporating the modified thermal theories. The rheological characteristics of human blood are justified by using the Casson fluid model. The thermal results are further supported with nonlinear radiated model and heat generation applications. More realistic convective thermal constraints for inspection of thermal simulations. After expressing the governing model in nonlinear differential equations, the numerical computations are performed via shooting scheme. The relative comparative thermal performances current model is examined for mono nanofluid TiO2/blood, hybrid nanoparticles CuO−TiO2/blood and tri-hybrid nanofluid TiO2−CuO−SiO2/blood. It has been predicted that enhancement in nanoparticles volume fraction increases the thermal phenomenon and heat transfer characteristics. In contrast, increment in Prandtl number and relaxation time parameter controls the heat transfer efficiency, indicating thermal resistance with tri hybrid nanofluid. Furthermore, thermal performance of tri nanofluid is more efficient as compared to mono and hybrid nanofluids. The simulated findings preserve significance in biomedical applications, especially in improving the drug delivery systems and enhancing thermal managements in hyperthermia treatments.http://www.sciencedirect.com/science/article/pii/S2214157X25004952Tri-hybrid nanofluidCasson fluidCattaneo-christov modelNonlinear radiationComparative thermal analysisBiomedical applications
spellingShingle Mohamed Arbi Khlifi
Faisal Mahroogi
Iskander Tlili
Thermal insight to magnetized tri hybrid nanofluid (CuO-TiO2-SiO2)/blood with nonlinear radiated Effects: Applications to hyperthermia cancer treatment
Case Studies in Thermal Engineering
Tri-hybrid nanofluid
Casson fluid
Cattaneo-christov model
Nonlinear radiation
Comparative thermal analysis
Biomedical applications
title Thermal insight to magnetized tri hybrid nanofluid (CuO-TiO2-SiO2)/blood with nonlinear radiated Effects: Applications to hyperthermia cancer treatment
title_full Thermal insight to magnetized tri hybrid nanofluid (CuO-TiO2-SiO2)/blood with nonlinear radiated Effects: Applications to hyperthermia cancer treatment
title_fullStr Thermal insight to magnetized tri hybrid nanofluid (CuO-TiO2-SiO2)/blood with nonlinear radiated Effects: Applications to hyperthermia cancer treatment
title_full_unstemmed Thermal insight to magnetized tri hybrid nanofluid (CuO-TiO2-SiO2)/blood with nonlinear radiated Effects: Applications to hyperthermia cancer treatment
title_short Thermal insight to magnetized tri hybrid nanofluid (CuO-TiO2-SiO2)/blood with nonlinear radiated Effects: Applications to hyperthermia cancer treatment
title_sort thermal insight to magnetized tri hybrid nanofluid cuo tio2 sio2 blood with nonlinear radiated effects applications to hyperthermia cancer treatment
topic Tri-hybrid nanofluid
Casson fluid
Cattaneo-christov model
Nonlinear radiation
Comparative thermal analysis
Biomedical applications
url http://www.sciencedirect.com/science/article/pii/S2214157X25004952
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AT faisalmahroogi thermalinsighttomagnetizedtrihybridnanofluidcuotio2sio2bloodwithnonlinearradiatedeffectsapplicationstohyperthermiacancertreatment
AT iskandertlili thermalinsighttomagnetizedtrihybridnanofluidcuotio2sio2bloodwithnonlinearradiatedeffectsapplicationstohyperthermiacancertreatment