The Protective Effects of MSC-Derived Exosomes Against Chemotherapy-Induced Parotid Gland Cytotoxicity

Conclusion: Within the limitations of the current study, BMMSC-derived exosomes have the potential to counteract the cytotoxic effects of 5-FU on the parotid glands of rats in vivo. Further studies are deemed necessary to simulate clinical scenarios.

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Bibliographic Details
Main Authors: Mahmoud M. Bakr, Mahmoud Al Ankily, Mohamed Shamel
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/ijod/5517092
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Summary:Conclusion: Within the limitations of the current study, BMMSC-derived exosomes have the potential to counteract the cytotoxic effects of 5-FU on the parotid glands of rats in vivo. Further studies are deemed necessary to simulate clinical scenarios.
ISSN:1687-8736