Psychological flexibility mediates the long-term impact of adverse interpersonal experiences in childhood and adolescence

Abstract Background Early exposure to interpersonal adverse events, such as traumatic childhood events or exposure to bullying, abuse, or harassment, can impact an adult’s psychological functioning. The negative effects on quality of life and the increased risk of psychopathological outcomes may und...

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Main Authors: Leonardo Fazio, Cristina Semeraro, Teresa Claudia Pennacchio, Martina Grazia Asselti, Marianna Russo, Rosalinda Cassibba, Alessandro Bertolino, Antonio Rampino, Ignazio Grattagliano, Giulio Pergola, Linda Antonella Antonucci
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Language:English
Published: BMC 2025-08-01
Series:BMC Psychology
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Online Access:https://doi.org/10.1186/s40359-025-03297-5
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author Leonardo Fazio
Cristina Semeraro
Teresa Claudia Pennacchio
Martina Grazia Asselti
Marianna Russo
Rosalinda Cassibba
Alessandro Bertolino
Antonio Rampino
Ignazio Grattagliano
Giulio Pergola
Linda Antonella Antonucci
author_facet Leonardo Fazio
Cristina Semeraro
Teresa Claudia Pennacchio
Martina Grazia Asselti
Marianna Russo
Rosalinda Cassibba
Alessandro Bertolino
Antonio Rampino
Ignazio Grattagliano
Giulio Pergola
Linda Antonella Antonucci
author_sort Leonardo Fazio
collection DOAJ
description Abstract Background Early exposure to interpersonal adverse events, such as traumatic childhood events or exposure to bullying, abuse, or harassment, can impact an adult’s psychological functioning. The negative effects on quality of life and the increased risk of psychopathological outcomes may underscore long-lasting vulnerabilities. Psychological flexibility is defined as the ability to be present in the moment and to pursue one’s values, and it can facilitate coping with adverse events occurring in the present. An open question is whether psychological flexibility may contribute to reducing the long-term consequences of exposure to early adversities. The relevance of this research is that psychological flexibility is modifiable through intervention. The present study investigated the potential role of psychological flexibility in modulating the relationship between early exposure to interpersonal adverse events and two outcomes in young adults: quality of life and psychological symptomatology. Methods We recruited one hundred and nine women aged 19–21 years. Exposure to adverse interpersonal events was assessed with the Childhood Trauma Questionnaire and the Bullying Scale; quality of life and psychological symptomatology were measured with the World Health Organization Quality of Life Scale and the Symptom checklist-90, respectively; psychological flexibility was assessed with the Multidimensional Psychological Flexibility Inventory. Results The frequency of adverse interpersonal events was associated with lower quality of life and greater psychological symptoms. Psychological flexibility mediated the relationship between the frequency of interpersonal adverse events and measures of quality of life, with an indirect effect explaining 18–42% of the total effect. Similarly, psychological flexibility mediated between the frequency of interpersonal adverse events and psychological symptomatology, with an indirect effect explaining 21–22% of the total effect. Conclusion The present study evaluates the impact of exposure to interpersonal adverse events on different aspects of quality of life and psychological symptomatology. The results suggest that psychological flexibility mediates the long-term repercussions of interpersonal adversity. As psychological flexibility is a modifiable skill, interventions aimed at enhancing it in individuals with early exposure to adverse interpersonal events, such as traumatic childhood events, bullying, abuse, or harassment, could be used to reduce the long-term effects of past adversities.
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spelling doaj-art-532412f43398475b9d254d9c1237ba442025-08-20T04:03:17ZengBMCBMC Psychology2050-72832025-08-0113111310.1186/s40359-025-03297-5Psychological flexibility mediates the long-term impact of adverse interpersonal experiences in childhood and adolescenceLeonardo Fazio0Cristina Semeraro1Teresa Claudia Pennacchio2Martina Grazia Asselti3Marianna Russo4Rosalinda Cassibba5Alessandro Bertolino6Antonio Rampino7Ignazio Grattagliano8Giulio Pergola9Linda Antonella Antonucci10Department of Medicine and Surgery, LUM University – Casamassima (Bari)Department of Education, Psychology, Communication, University of Bari Aldo MoroDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo MoroDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo MoroDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo MoroDepartment of Education, Psychology, Communication, University of Bari Aldo MoroDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo MoroDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo MoroDepartment of Education, Psychology, Communication, University of Bari Aldo MoroDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo MoroDepartment of Translational Biomedicine and Neuroscience, University of Bari Aldo MoroAbstract Background Early exposure to interpersonal adverse events, such as traumatic childhood events or exposure to bullying, abuse, or harassment, can impact an adult’s psychological functioning. The negative effects on quality of life and the increased risk of psychopathological outcomes may underscore long-lasting vulnerabilities. Psychological flexibility is defined as the ability to be present in the moment and to pursue one’s values, and it can facilitate coping with adverse events occurring in the present. An open question is whether psychological flexibility may contribute to reducing the long-term consequences of exposure to early adversities. The relevance of this research is that psychological flexibility is modifiable through intervention. The present study investigated the potential role of psychological flexibility in modulating the relationship between early exposure to interpersonal adverse events and two outcomes in young adults: quality of life and psychological symptomatology. Methods We recruited one hundred and nine women aged 19–21 years. Exposure to adverse interpersonal events was assessed with the Childhood Trauma Questionnaire and the Bullying Scale; quality of life and psychological symptomatology were measured with the World Health Organization Quality of Life Scale and the Symptom checklist-90, respectively; psychological flexibility was assessed with the Multidimensional Psychological Flexibility Inventory. Results The frequency of adverse interpersonal events was associated with lower quality of life and greater psychological symptoms. Psychological flexibility mediated the relationship between the frequency of interpersonal adverse events and measures of quality of life, with an indirect effect explaining 18–42% of the total effect. Similarly, psychological flexibility mediated between the frequency of interpersonal adverse events and psychological symptomatology, with an indirect effect explaining 21–22% of the total effect. Conclusion The present study evaluates the impact of exposure to interpersonal adverse events on different aspects of quality of life and psychological symptomatology. The results suggest that psychological flexibility mediates the long-term repercussions of interpersonal adversity. As psychological flexibility is a modifiable skill, interventions aimed at enhancing it in individuals with early exposure to adverse interpersonal events, such as traumatic childhood events, bullying, abuse, or harassment, could be used to reduce the long-term effects of past adversities.https://doi.org/10.1186/s40359-025-03297-5Psychological flexibilityAdverse childhood experienceChildhood traumaACEBullying victimizationBullying
spellingShingle Leonardo Fazio
Cristina Semeraro
Teresa Claudia Pennacchio
Martina Grazia Asselti
Marianna Russo
Rosalinda Cassibba
Alessandro Bertolino
Antonio Rampino
Ignazio Grattagliano
Giulio Pergola
Linda Antonella Antonucci
Psychological flexibility mediates the long-term impact of adverse interpersonal experiences in childhood and adolescence
BMC Psychology
Psychological flexibility
Adverse childhood experience
Childhood trauma
ACE
Bullying victimization
Bullying
title Psychological flexibility mediates the long-term impact of adverse interpersonal experiences in childhood and adolescence
title_full Psychological flexibility mediates the long-term impact of adverse interpersonal experiences in childhood and adolescence
title_fullStr Psychological flexibility mediates the long-term impact of adverse interpersonal experiences in childhood and adolescence
title_full_unstemmed Psychological flexibility mediates the long-term impact of adverse interpersonal experiences in childhood and adolescence
title_short Psychological flexibility mediates the long-term impact of adverse interpersonal experiences in childhood and adolescence
title_sort psychological flexibility mediates the long term impact of adverse interpersonal experiences in childhood and adolescence
topic Psychological flexibility
Adverse childhood experience
Childhood trauma
ACE
Bullying victimization
Bullying
url https://doi.org/10.1186/s40359-025-03297-5
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