Effect of Intravenous Magnesium Sulfate on Improving the Quality of Anesthesia for Appendectomy Candidates under Regional Anesthesia
Background: One of the major challenges in surgery is pain control after surgery. The present study was conducted with the aim of investigating the role of magnesium sulfate in improving the quality of anesthesia in patients who are candidates for appendectomy surgery. Methods: In this clinical tria...
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Ardabil University of Medical Sciences
2024-07-01
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| Series: | Journal of Ardabil University of Medical Sciences |
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| Online Access: | http://jarums.arums.ac.ir/article-1-2444-en.pdf |
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| author | Mahzad Yousefian Ali Mohammadian-Erdi Afshan Sharghi Mina Deldadeh Moghaddam |
| author_facet | Mahzad Yousefian Ali Mohammadian-Erdi Afshan Sharghi Mina Deldadeh Moghaddam |
| author_sort | Mahzad Yousefian |
| collection | DOAJ |
| description | Background: One of the major challenges in surgery is pain control after surgery. The present study was conducted with the aim of investigating the role of magnesium sulfate in improving the quality of anesthesia in patients who are candidates for appendectomy surgery.
Methods: In this clinical trial study, 42 people in the control group and 42 people in the intervention group were randomly included. For the intervention group, 50 mg/kg of magnesium sulfate was injected and for the control group, the same amount of distilled water was injected as a placebo. After surgery, the patients were examined for pain, nausea and vomiting, anxiety, blood pressure and heart rate, and the satisfaction of the surgeon in terms of muscle relaxation. Collected data were analyzed in SPSS-26 by statistical methods and p<0.05 was considered as significant level.
Results: The average pain of the patients in the first, third, sixth and twelfth hours of the study in the intervention group with 1.4, 2.66, 3.3 and 3.19 were significantly lower than the control group. In terms of relaxation, a significant difference was observed between the two groups in the first, third, sixth, twelfth and eighteenth hours of the study. In the examination of nausea and vomiting of patients, no significant difference was observed between the two groups. During surgery, a significant difference was observed in patients receiving magnesium sulfate compared to the control group in terms of surgeon satisfaction.
Conclusion: Magnesium sulfate was effective in controlling patients' pain and anxiety and surgeon's satisfaction during surgery, but it was not effective in controlling patients' nausea and vomiting. |
| format | Article |
| id | doaj-art-53068e1957634de7a59210ed95776b7e |
| institution | Kabale University |
| issn | 2228-7280 2228-7299 |
| language | fas |
| publishDate | 2024-07-01 |
| publisher | Ardabil University of Medical Sciences |
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| series | Journal of Ardabil University of Medical Sciences |
| spelling | doaj-art-53068e1957634de7a59210ed95776b7e2025-01-16T07:22:31ZfasArdabil University of Medical SciencesJournal of Ardabil University of Medical Sciences2228-72802228-72992024-07-01242210220Effect of Intravenous Magnesium Sulfate on Improving the Quality of Anesthesia for Appendectomy Candidates under Regional AnesthesiaMahzad Yousefian0Ali Mohammadian-Erdi1Afshan Sharghi2Mina Deldadeh Moghaddam3 Department of Anethesiology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Department of Anethesiology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Department of Community Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran General Practitioner, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran. Background: One of the major challenges in surgery is pain control after surgery. The present study was conducted with the aim of investigating the role of magnesium sulfate in improving the quality of anesthesia in patients who are candidates for appendectomy surgery. Methods: In this clinical trial study, 42 people in the control group and 42 people in the intervention group were randomly included. For the intervention group, 50 mg/kg of magnesium sulfate was injected and for the control group, the same amount of distilled water was injected as a placebo. After surgery, the patients were examined for pain, nausea and vomiting, anxiety, blood pressure and heart rate, and the satisfaction of the surgeon in terms of muscle relaxation. Collected data were analyzed in SPSS-26 by statistical methods and p<0.05 was considered as significant level. Results: The average pain of the patients in the first, third, sixth and twelfth hours of the study in the intervention group with 1.4, 2.66, 3.3 and 3.19 were significantly lower than the control group. In terms of relaxation, a significant difference was observed between the two groups in the first, third, sixth, twelfth and eighteenth hours of the study. In the examination of nausea and vomiting of patients, no significant difference was observed between the two groups. During surgery, a significant difference was observed in patients receiving magnesium sulfate compared to the control group in terms of surgeon satisfaction. Conclusion: Magnesium sulfate was effective in controlling patients' pain and anxiety and surgeon's satisfaction during surgery, but it was not effective in controlling patients' nausea and vomiting.http://jarums.arums.ac.ir/article-1-2444-en.pdfmagnesium sulfateappendectomyanesthesia |
| spellingShingle | Mahzad Yousefian Ali Mohammadian-Erdi Afshan Sharghi Mina Deldadeh Moghaddam Effect of Intravenous Magnesium Sulfate on Improving the Quality of Anesthesia for Appendectomy Candidates under Regional Anesthesia Journal of Ardabil University of Medical Sciences magnesium sulfate appendectomy anesthesia |
| title | Effect of Intravenous Magnesium Sulfate on Improving the Quality of Anesthesia for Appendectomy Candidates under Regional Anesthesia |
| title_full | Effect of Intravenous Magnesium Sulfate on Improving the Quality of Anesthesia for Appendectomy Candidates under Regional Anesthesia |
| title_fullStr | Effect of Intravenous Magnesium Sulfate on Improving the Quality of Anesthesia for Appendectomy Candidates under Regional Anesthesia |
| title_full_unstemmed | Effect of Intravenous Magnesium Sulfate on Improving the Quality of Anesthesia for Appendectomy Candidates under Regional Anesthesia |
| title_short | Effect of Intravenous Magnesium Sulfate on Improving the Quality of Anesthesia for Appendectomy Candidates under Regional Anesthesia |
| title_sort | effect of intravenous magnesium sulfate on improving the quality of anesthesia for appendectomy candidates under regional anesthesia |
| topic | magnesium sulfate appendectomy anesthesia |
| url | http://jarums.arums.ac.ir/article-1-2444-en.pdf |
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